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26-Jun-2024

How Life Science Research Is Teaming up With Advanced Technology To Help Us Live Longer

Summary

Scientists have predicted that the first person who will live to 150 has already been born.1 While this number may sound far-fetched, researchers have developed several interventions to extend the human lifespan. Innovations such as artificial intelligence, stem cell therapy, precision medicine, and telemedicine are changing how healthcare providers diagnose and treat illnesses, ultimately increasing the average life expectancy. But how exactly is technology helping us live longer?
  • Author Name: Beth Rush
  • Author Email: beth@bodymind.com
Editor: PharmiWeb Editor Last Updated: 26-Jun-2024

Scientists have predicted that the first person who will live to 150 has already been born.1 While this number may sound far-fetched, researchers have developed several interventions to extend the human lifespan. Innovations such as artificial intelligence, stem cell therapy, precision medicine, and telemedicine are changing how healthcare providers diagnose and treat illnesses, ultimately increasing the average life expectancy. But how exactly is technology helping us live longer?

The History of Aging

It’s no secret that these days, people are living longer than ever before. Throughout history, the average human life span has seen significant fluctuations due to various factors such as diet, disease, geographical location, and living conditions. In ancient times, people rarely lived beyond their 30s or 40s. For instance, in Ancient Greece, the average life expectancy hovered around 37-43 years based on skeletal evidence.2

These shorter life spans were largely due to high infant mortality rates and the prevalence of diseases that couldn’t be treated effectively. In the Middle Ages, life expectancy didn’t improve much. The average life expectancy remained short, often because of harsh living conditions, frequent wars, and the lack of medical knowledge.

It wasn’t until the 19th and 20th centuries that you would notice a significant increase in life expectancy. This period saw major medical advances, such as vaccine and antibiotic development and improved surgical techniques. Public health measures, including better sanitation and cleaner water supplies, also played a crucial role. Despite these improvements, life expectancy was still far from what it is today, with many people living into their 50s and 60s in developed countries.3

Today, you live in an era where the average life span has dramatically increased. Common conditions like colds and flu used to wipe out thousands of people, but thanks to modern medicine people survive multiple bouts of viral infections each year. In many developed countries, it’s common for people to live into their 80s and beyond. This remarkable life extension is primarily due to medical science advancements, better nutrition, higher education quality, and improved living conditions.

Vaccinations, modern healthcare, and a better understanding of diseases have all reduced mortality rates. Moreover, you can benefit from a wealth of knowledge on healthy living practices and the availability of technology that monitors and improves health. As a result, you can expect to live much longer and healthier lives compared to your ancestors.

How Is Technology Helping Us Live Longer?

Technology undeniably plays a central role in extending human life span and improving overall health. By integrating advances in various fields such as genomics, artificial intelligence, robotics, and personalized medicine, we are witnessing a healthcare revolution that promises to enhance the quality and longevity of life. Below are some key ways technology is helping us live longer.

Genomics and Precision Medicine

In recent years, life science research has made groundbreaking improvements in genomics and precision medicine, significantly impacting human health and longevity. Genomics — the study of an organism’s complete set of DNA — has revolutionized our understanding of the genetic basis of diseases.

By mapping the human genome, scientists have identified genes associated with various conditions, allowing for earlier detection and more effective interventions. This knowledge enables you to understand your genetic predispositions and take preventive measures to mitigate health risks, thus extending your life span.

Precision medicine builds on the insights genomics provides, offering personalized healthcare tailored to an individual’s genetic makeup, lifestyle, and environment. Instead of a one-size-fits-all approach, precision medicine aims to provide treatments specifically designed to work best for you.4 For example, if you have a particular genetic mutation that increases your risk for cancer, doctors can develop a targeted therapy to address that mutation. This innovation can lead to better health outcomes and longer life expectancy.

These technologies have also facilitated novel therapy development and previously unimaginable interventions. Techniques like CRISPR gene editing allow scientists to modify genes associated with diseases, potentially curing genetic disorders at their source.5

Personalized medicine also extends to pharmacogenomics, where your genetic profile can guide the selection and dosage of medications, ensuring you receive the most effective and safe treatment.6 These innovations showcase a paradigm shift in healthcare, where the focus is now on prevention, early detection, and personalized treatment, ultimately contributing to increased longevity and quality of life.

Stem Cell Therapy

Stem cell therapy is one of the most promising advances in modern medicine. It offers the potential to treat various diseases and injuries researchers previously considered untreatable. Stem cells are unique because they can develop into different types of cells in the body, such as muscle or nerve cells.

This capability allows them to replace damaged or diseased cells, prompting tissue repair and regeneration. For example, stem cell therapy can restore function in conditions like spinal cord injuries or heart disease by regenerating these damaged tissues. This offers hope for recovery where conventional treatments fall short.7

Stem cell therapy application is expanding rapidly, with clinical trials and treatments being developed for numerous conditions. In neurodegenerative diseases, such as Parkinson's and Alzheimer’s, researchers are exploring stem cells to replace lost neurons and restore neurological function.7

Similarly, in diabetes cases, scientists use stem cell therapy to regenerate insulin-producing cells in the pancreas. This potentially offers a cure for patients. Moreover, scientists are using stem cells in regenerative medicine to treat burns and wounds, improving patients’ quality of life and extending their life span.8

Artificial Intelligence in Healthcare

Artificial Intelligence (AI) is of particular interest in various industries, particularly in the healthcare sector. It's one of the key ways technology can help us live longer. AI is revolutionizing healthcare by enhancing diagnostics and personalized treatments, streamlining medical research, and assisting with tasks like scheduling appointments.

AI algorithms can analyze large medical datasets much faster than humans can — and accurately. This capability allows for earlier and more accurate disease diagnosis, enabling timely interventions to improve patient outcomes.

For instance, AI-powered imaging tools can detect cancers at much earlier stages than traditional methods, leading to more effective treatment options and higher survival rates. One such tool is iStar (Inferring Super-Resolution Tissue Architecture), which provides incredibly detailed images of individual cells, allowing researchers to identify cancer cells that would otherwise have been invisible.9

AI also allows doctors to personalize treatments. Machine learning models can analyze a patient’s genetic information, lifestyle, and medical history to predict how they will respond to different treatments. This way, healthcare professionals can choose the most effective therapies with fewer side effects.

Researchers are using AI tools to discover new drugs faster by predicting which compounds will be effective against specific diseases, accelerating the development of new treatments. AI also allows scientists to discover drugs at a lower cost, enabling them to direct capital elsewhere.

“So it’s not only helping speed up the drug development, but also it helps with lowering the cost of running a company. That means you can deploy more of the capital towards drug development and find more cures faster.” said Arda Ural, Ernst & Young’s America's health and life sciences industry market leader. [SOURCE: https://www.cnbc.com/2024/03/24/nvidias-ai-ambitions-in-medicine-and-health-care-are-becoming-clear.html]10

Telemedicine and Remote Monitoring

Telemedicine and remote monitoring are transforming healthcare by making medical services more accessible and it’s one of the more simple ways technology is helping us live longer. Through telemedicine, you can consult your healthcare providers from the comfort of your home, reducing the need for travel and ensuring timely medical advice. This is especially beneficial for those in remote areas or with mobility challenges.11

Telemedicine can manage chronic diseases more effectively by facilitating early diagnosis and immediate consultation, preventing complications that could shorten life. For instance, regular virtual check-ups can keep conditions like high blood pressure and diabetes under control, reducing the risk of serious health events such as strokes or heart attacks.

On the other hand, remote monitoring allows healthcare providers to continuously track your health metrics using wearable devices and home-based sensors. Common wearable devices include cell phones and smartwatches, which can read heart rate, count steps, measure breathing rate, and detect sleeping patterns. However, emerging technologies take this a step further. Recent innovations include sunglasses that detect vision performance, which doctors can use to identify concussions and assess eyesight.12

Robotics in Surgery

Robotics in surgery is revolutionizing medicine, significantly extending life expectancy by enhancing precision, safety, and outcomes of surgical procedures. Robot-assisted surgeries allow surgeons to perform complex and delicate operations with greater accuracy.

These robotic systems provide high-definition, 3D views of the surgical site and instruments, reducing the risk of human error. This precision is advantageous for procedures involving critical areas like the brain, heart, and spine, where even minor eros can have severe consequences.

Additionally, robotic surgery typically results in less invasive procedures, leading to smaller incisions and shorter recovery times. Patients who undergo robot-assisted surgeries often experience fewer complications and a quicker return to their daily lives.13 For instance, in cancer treatments, the precision ensures more effective tumor removal while preserving surrounding healthy tissue, improving long-term survival rates.

Enhanced recovery processes also mean patients are less likely to experience postoperative infections or other complications. This allows them to lead longer, healthier lives. 13

Challenges and Future Implications

Although technology is undoubtedly helping us live longer, there are significant challenges in the quest to extend the human life span. One of the primary challenges is the ethical and regulatory concerns that arise with new technologies such as gene editing and AI. The potential for misuse or unintended consequences requires stringent oversight and ethical guidelines to ensure these technologies are used responsibly.14

The high costs associated with cutting-edge treatments and technologies can create access disparities, meaning that the benefits might not be equally available to all populations.15 Overcoming these challenges is crucial to ensuring life-extending technologies contribute to overall public health and longevity.

Despite these challenges, the future implications are promising. As researchers and technologists collaborate more closely, we can expect breakthroughs in precision medicine. This collaboration can lead to the development of more effective and targeted therapies, reducing the current trial-and-error approach in medicine.4 For example, genomic and AI innovations can predict how patients will respond to treatments, optimizing health care delivery and improving outcomes.

Looking ahead, this collaboration holds the potential to transform our understanding and management of aging. Innovations like regenerative medicine and nanotechnology which could enable precise drug delivery at the cellular level, are on the horizon. These technologies could drastically reduce the incidence of age-related diseases and improve the quality of life for the elderly.

Lastly, the ongoing development of wearable health devices and remote monitoring systems ensures healthcare can become more proactive and personalized. By continuously gathering and analyzing health data, these innovations can provide real-time insights and interventions, helping humans extend their life spans.

The Promise of Modern Medicine

While many access challenges and ethical dilemmas remain, advanced technology is reshaping healthcare delivery. As these technologies evolve and become more integrated into everyday healthcare, they promise a future where living longer and healthier lives becomes the norm rather than the exception.

References

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  2. Malamitsi‐Puchner, A. and Konstantakos, I.M. (2023) ‘Evidence, hints and assumptions for late pregnancy in the ancient Mediterranean and Near East’, Acta Paediatrica, 112(7), pp. 1371–1377. doi:10.1111/apa.16781.
  3. O’Neill, A. (2024) Global life expectancy by region 1820-2020, Statista. Available at: https://www.statista.com/statistics/1302736/global-life-expectancy-by-region-country-historical/ (Accessed: 19 June 2024).
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  5. What are genome editing and CRISPR-Cas9?: Medlineplus Genetics (2022) MedlinePlus. Available at: https://medlineplus.gov/genetics/understanding/genomicresearch/genomeediting/ (Accessed: 19 June 2024).
  6. What is Pharmacogenomics?: Medlineplus Genetics (2022) MedlinePlus. Available at: https://medlineplus.gov/genetics/understanding/genomicresearch/pharmacogenomics/ (Accessed: 19 June 2024).
  7. Zhang Y, Chen H, Huang C. Optimizing health-span: advances in stem cell medicine and longevity research. Med Rev (2021). 2023;3(4):351-355. Published 2023 Oct 10. doi:10.1515/mr-2023-0040
  8. Zeng, N. et al. (2022) ‘Adipose stem cell-based treatments for wound healing’, Frontiers in Cell and Developmental Biology, 9. doi:10.3389/fcell.2021.821652.
  9. AI tool brings Precision Pathology for cancer into focus (2024) AI Tool Brings Precision Pathology for Cancer Into Focus. Available at: https://www.pennmedicine.org/news/news-releases/2024/january/ai-tool-brings-precision-pathology-for-cancer-into-focus (Accessed: 19 June 2024).
  10. Castillo, M. (2024) Nvidia’s AI ambitions in medicine and health care are becoming clear, CNBC. Available at: https://www.cnbc.com/2024/03/24/nvidias-ai-ambitions-in-medicine-and-health-care-are-becoming-clear.html (Accessed: 19 June 2024).
  11. Chandrasekhar, K. (2023) Telemedicine can deliver healthcare to remote communities in Asia. here’s how, World Economic Forum. Available at: https://www.weforum.org/agenda/2023/08/telemedicine-collaborations-bridge-healthcare-access-asia-underserved-communities/ (Accessed: 19 June 2024).
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