The Effect of Probiotics for the Gut Health

There are trillions of microbes inhabiting the human intestine. These microbes gradually reach a balance of types and numbers during the process of reproduction, and this balance is closely related to the body's normal metabolism. Once the structure of the intestinal flora becomes imbalanced, various metabolic diseases will follow. The probiotics multiply in large quantities in the intestine, which can adjust the disordered intestinal flora structure and improve the body's immune ability, thereby helping to restore health.

There are a large number of symbiotic flora in the normal human body. Most of these bacteria are parasitic in the human intestine, more than 1,000 trillion, which is 10 times the total number of human cells. The number of microbial genes is about 3 million, which is about 100 times the number of genes in the human genome. Such a large number of genes can help microorganisms adapt to the changing environment, and at the same time form an inseparable and mutually beneficial symbiosis with the human body. Studies have found that different intestinal microbial structures and compositions affect the host's nutrient processing, energy balance, immune function, gastrointestinal development and many other important physiological activities. At the same time, studies have found that the structure of the intestinal flora of patients with metabolic diseases such as diabetes, obesity, and hypertension is different from that of healthy people.

Probiotics affect the health of the human body by changing the composition of the intestinal microflora, and may also help the treatment of certain diseases. A large number of studies have found that direct consumption of capsules rich in probiotic strains and fermented dairy products can deliver a large number of active probiotic strains to the human intestines, thereby directly and effectively affecting the human intestinal microbial composition.

Probiotic is a general term for living beneficial microorganisms that colonize the human intestines and produce definite health effects. Probiotics mainly include Lactobacillus and Bifidobacterium. Their probiotic effects are mainly achieved by directly or indirectly adjusting the composition of the host’s intestinal microbes and activating the host’s endogenous microbiota or the activity of the immune system.

Oral probiotics can cure or alleviate a variety of gastrointestinal or gastrointestinal-related diseases. Current studies have confirmed that oral probiotics can help relieve lactose intolerance, prevent or cure gastroenteritis, antibiotic-related diarrhea, travel diarrhea, constipation and intestinal infections. At the same time, it can inhibit the colonization of harmful microorganisms in the host's intestine, and has a good preventive and therapeutic effect on intestinal related diseases such as irritable bowel syndrome, inflammatory bowel disease and colon cancer.

The effects of probiotics on the intestinal flora can be divided into direct effects and indirect effects. Direct influence refers to the fact that the intake of certain probiotics can directly change the inherent flora in the intestinal tract. Indirect effects mean that the intake of probiotics may affect the metabolism of certain intestinal flora, thereby changing the content of short-chain fatty acids (SCFA) and total bile acids (TBA) in the intestines, as well as the activity of bacterial enzymes and the absorption of mineral ions.

1. The intake of probiotics affects the structure of intestinal flora

By promoting the reproduction of beneficial bacteria and inhibiting the growth of harmful bacteria, probiotics not only change the host's intestinal flora, but also exert their own probiotic properties.

1. The intake of probiotics affects the level of short-chain fatty acid metabolism

Short-chain fatty acids refer to organic fatty acids with 1 to 6 carbon chains. Usually short-chain fatty acids include acetic acid, propionic acid and butyric acid, which are the main products of human colonic bacterial fermentation.

Clinical studies have shown that short-chain fatty acids can maintain the shape and function of the intestinal tract. It also has a certain therapeutic effect, which can relieve and treat various intestinal surgical diseases such as diversion colitis, distal ulcerative colitis, pouchitis, radiation colitis, short bowel syndrome and so on.

1. The intake of probiotics affects the metabolism of total bile acid

Bile Acids is a general term for a large class of cholanoic acid, which exists in the form of sodium or potassium salt. They are amphipathic cholesterol metabolites, synthesized in the liver, stored in the gallbladder, and then released into the small intestine.

Studies have shown that secondary bile acids are the promoters of malignant tumors and are harmful to the human body. The intake of certain lactobacilli and bifidobacteria can reduce the content of this substance in feces.

1. The intake of probiotics affects the activity of intestinal bacterial enzymes

When malignant tumors occur in the body, the enzyme activity in the stool increases. Most studies have shown that the intake of probiotics can reduce the activity of this enzyme, which indirectly indicates that probiotics have an anti-cancer effect to a certain extent.

Studies have found that adding probiotics and prebiotics to the daily diet can significantly increase the absorption of calcium ions in volunteers. The mechanism may be that the intake of probiotics or probiotics increases the length of intestinal villi and the depth of crypts, thereby increasing the absorption area of mineral ions, so calcium ions can be better absorbed. With the continuous expansion of business areas and scale, Creative Enzymes has set foot in other areas and established a sound probiotic production and supply chain. Based on our high-quality products and services, as well as the unique advantages of large-scale production, our probiotic products are widely favored by industrial customers and scientific research customers.