Isothermal Nucleic Acid Amplification Technology (INAAT) Market to Surpass US$ 3,622.0 Mn by 2027, Owing to R&D in INAAT

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According to the Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market Report, by Product Type (Instruments and Reagents & Kits), by Technology (Helicase Dependent Amplification (HAD),  Nicking Enzyme Amplification Reaction (NEAR), Nucleic Acid Sequence-based Amplification (NASBNA), Transcription Medicated Amplification (TMA), Single Primer Isothermal Amplification (SPIA), and Loop-mediated Isothermal Amplification (LAMP)), by Application (Infectious Disease Diagnostics, Blood Screening, Others), by End User (Academic and Research Institutes, Diagnostic Laboratories, and Others), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa), published by Coherent Market Insights, the global isothermal nucleic acid amplification technology (INAAT) market was valued at US$ 1,900.6 million in 2019, and is expected to exhibit a CAGR of 8.3% during the forecast period (2019 – 2027).

Isothermal nucleic acid amplification technology (INAAT) is used to detect malaria infections. It is used for qualitative or quantitative parasite detection, to determine the multiplicity of infection, in genotyping to distinguish recrudescence from reinfection, and to detect drug resistance mutations.

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R&D in INAAT is expected to boost growth of the global isothermal nucleic acid amplification technology (INAAT) market over the forecast period. For instance, in June 2019, researchers from Tokyo Institute of Technology, Abbott Japan Co., Ltd, and the University of Electro-Communications developed a new way of amplifying DNA, known as DNA L-TEAM (Low-temperature Amplification). This technique is used to amplify DNA segments and it works at body temperature (37°C/98.6°F).

Moreover, launch of new isothermal kits for molecular diagnosis of diseases is also expected to aid in growth of the global isothermal nucleic acid amplification technology (INAAT) market. For instance, in January 2018, Mast Diagnostics launched new Isoplex DNA Lyo isothermal amplification kit. Isoplex DNA Lyo Kit is based on loop-mediated isothermal amplification (LAMP) technology. It is a rapid nucleic acid amplification method associated with polymerase chain reaction.

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Among regions, Europe is expected to witness significant growth in the global isothermal nucleic acid amplification technology (INAAT) market over the forecast period. This is attributed to launch of molecular diagnostics workflow. For instance, in April 2018, Altona Diagnostics GmbH launched new CE-IVD marked AltoStar Molecular Diagnostic Workflow. Under this workflow, company launched various CE-marked real-time polymerase chain reaction (PCR) kits such as Parvorvirus B19.

Key players in the market are focused on R&D in INAAT. For instance, in December 2019, Genomtec received Horizon 2020 SME phase I grant for Genomtec Tumor, a device which works on the principle of streamlined nucleic acid amplification technology (SNAAT) that uses photo-based technology for heating the reaction mixture and amplify specific fragments of nucleic acids specific to cancer.

Major players in the market are also focused on launching new products to expand their product portfolio. For instance, Genomtec announced to launch Genomtech ID, a device that operates on the principle of INAAT, in December 2021. The device consist of a reaction card, on which the biological material is applied and the card is inserted in the device. After diagnosis, the result is displayed on the screen in 20 minutes. The device is used to detect pathogens from biological materials in just 15 -20 minutes with a specificity close to 100%. Similarly, in October 2016, Arcis Biotechnology launched its DNA blood kit, which is used for in vitro diagnostic testing. This kit is also suitable for polymerase chain reaction (PCR) that is based on INAAT.

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Key Takeaways:

• The global isothermal nucleic acid amplification technology (INAAT) market is expected to exhibit a CAGR of 8.3% during the forecast period (2019-2027)
• R&D in INAAT is expected to boost growth of the global isothermal nucleic acid amplification technology (INAAT) market over the forecast period
• Major players operating in the global isothermal nucleic acid amplification technology (INAAT) market include, Alere Inc., Becton, Dickinson & Company, BioHelix Corporation, BioMerieux Biotechnology Company, Hologic Gene-Probe, QIAGEN Company, Thermo Fisher Scientific, Inc., Lucigen Corporation, Quidel Corporation, and NuGEN

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