Cancer Vaccines Market Growth Factors with Key Drivers Forecast From 2019-2026 | Industry Analysis By Key Players, And Upcoming Trends
Cancer is the second leading cause of morbidity and mortality worldwide. Gene mutation is a major cause of cancer. The disease can also be caused by inherited genes. Cancer can be divided into carcinoma, lymphomas, leukaemias, brain tumors, and sarcomas based on the type of cell the disease initiates in. According to World Health Organization (WHO), 2017, nearly 1 in 6 deaths is due to cancer globally and around 70% of deaths from cancer occur in low- and middle-income countries. Moreover, it is projected that for next two decades, 70% of new cases are expected to be diagnosed globally. Development of cancer vaccines can aid in substantially decreasing the number of cancer cases.
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Global Cancer Vaccines Market Taxonomy:
By Product Type:
- Preventive cancer vaccines
- Therapeutic cancer vaccines
By Technology:
- Subunit Vaccines
- Live Attenuated Vaccines
- Conjugate Vaccines
- Inactivated Vaccines
- Recombinant Vector Vaccines
- Viral Vector And DNA Cancer Vaccines
- Others
By Application:
- Cervical cancer
- Prostate cancer
- Others
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Increasing approval and launch of new vaccines for the treatment of different types of cancers is expected to boost growth of the cancer vaccines market over the forecast period
Key players in the market are focused on adopting M&A and collaboration strategies in order to expand their product portfolio. For instance, in 2017, Gilead Science Inc. acquired Kite Pharma Inc., which is involved in development of different type of immunotherapy and vaccines. In 2017, Treos Bio, collaborated with Pharmaceutical Product Development, LLC (PPD) to conduct its first-in-human clinical trial for its cancer vaccine for metastatic colorectal cancer.
Furthermore, BioNTech developed RNA vaccines for mutations caused due to cancer. RNA vaccine exposes cancer cell to antigen, which is recognized by the immune system. On the other hand, Scancell’s DNA vaccine forces cancerous cell to express two antigens – gp100 and TRP-2 stimulating a strong T cell response.
In 2017, Jonsson Comprehensive Cancer Center and the Brain Tumor Center at the University of California Los Angeles (UCLA), was designated a Specialized Program of Research Excellence (SPORE) by the National Cancer Institute. The program is expected to support research into prevention, detection, and treatment of cancers and will promote co-operation among scientist in different disciplines, and also help to translate basic research from laboratories to clinical trials more quickly and effectively. Such recognition by national organizations is expected to support research in cancer vaccines.
According to a research from University of Pittsburgh School of Medicine, in 2017, a high dose flu vaccine can be used to treat people aged between 54–64 years with chronic condition such as heart disease, lung disease, diabetes, and cancer. The study is recommended for clinical trials in geriatric population.
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Also, in 2017, Swiss Biotech, developed VXM01 — an attenuated bacterial vaccine modified to express vascular endothelial growth factor receptor-2 (VEGFR2), stimulates cytotoxic (killer) T cells, which will destroy cells in the vasculature feeding tumor and allow greater infiltration of immune cells. This vaccine is expected to be used for treatment in colorectal cancer and glioblastoma.
In August 2017, Imugene Limited announced the entry of its anti-cancer vaccine, HER-Vaxx for gastric cancer in 1b/2 clinical study and the phase 2 is expected to start soon.
Increasing prevalence and incidence of different cancers is expected to favor growth of the cancer vaccines market
According to WHO, in 2015, about 8.8 million people died from cancer. Moreover, tobacco related cancers was responsible for 22% deaths, lung cancer accounted for 1.69 million deaths, liver cancer led to 788,000 deaths. Colorectal, stomach, and breast cancer are estimated to cause 774,000, 754,000, and 571,000 deaths, worldwide. Increasing prevalence is a major driving factor to fuel growth of the cancer vaccines market.
Key players in the global cancer vaccines market include, Astrazeneca Plc. (Medimmune, LLC.), Glaxosmithkline Plc., Merck & Co., Inc., Sanofi Pasteur, Aduro BioTech Inc., Sanpower Group, Astellas Pharma Inc., CSL Limited, Pfizer Inc., and Serum Institute of India Pvt. Ltd.
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