Cell Banking Outsourcing Market Size Estimation, Top Key Players and Future Trends | Charles River Laboratories, Cryo-Cell International Inc., BioOutsource etc

Global Cell Banking Outsourcing Market – Insights

In cell banking, cells replicated and stored for the purpose of future use in stem cell R&D and stem cell therapy (SCT). Cell banking offers detailed characterization and avoids contamination of cell lines. It is also saves costs incurred by maintaining cells in cell culture. Cryoprotection agents such as 10% solution of DMSO are used to freeze cells in cryovials at -196 degrees Celsius. Master cell bank (MCB) and working cell bank (WCB) are the two types of cell banks. A MCB can be expanded to form WCB. MCB consists of pure cells that are used for replication of cells. WCB consists of thawed cells that are replicated in cell culture.

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Global Cell Banking Outsourcing Market: Drivers

Increasing adoption of SCT is expected to boost growth of the global cell banking outsourcing market over the forecast period. For instance, according to the World Network for Blood and Marrow Transplantation (WBMN), during 2006–2014, around one million hematopoietic stem cell transplantation were performed, which included removing stem cells from bone marrow or peripheral blood and proliferating and storing them in cell banks for later use in patients. Moreover, according to World Marrow Donor Association, 2016, SCT can be used in the treatment of over 100 diseases.

Moreover, R&D in immunotherapy is also expected to aid in growth of the market. Genetic modification of T cells, in vitro proliferation of T cells, and storing of T cells in cell banks are some of the task involved in immunotherapy. Moreover, the modified T cells are injected back into the patient’s body to produce immune response and eliminate tumors.

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Global Cell Banking Outsourcing Market: Restraints 

High expenditure is involved in storing of cells in cell banks, which is expected to hinder growth of the market. For instance, storage of cells in cell banks may cost around US$ 2,500 (on an average), annually.

Moreover, stringent regulations in cell banking are also expected to hamper growth of the market. For instance, in October 2017, the government of India put a temporary ban on commercial banking of stem cells derived from biological materials such as cord tissue, placenta, tooth extract and menstrual blood, in the absence of scientific evidence about its benefits. In Italy and France, storing of one’s cord blood is illegal. There are also issues pertaining with reimbursement for cell banking. For instance, in the U.S., insurance companies provide reimbursement for cord blood banking only when medically necessary. Such factors are expected to limit adoption of cell banking outsourcing.

Global Cell Banking Outsourcing Market: Opportunities 

Production of vaccines involve the use of viral cell banking and viral cell banking. Therefore, high demand for vaccines and other biologics is expected to create lucrative growth opportunity for players in the global cell banking outsourcing market.

Moreover, increasing R&D in gene therapy is also expected to aid in growth of the market.

Global Cell banking Outsourcing Market Taxonomy

On the basis of type of bank, the global cell banking outsourcing market is segmented into:

• Master Cell Banking
• Working Cell Banking
• Viral Cell Banking

On the basis of type of cell, the global cell banking outsourcing market is segmented into:

• Stem Cell Banking
  • Cord Stem Cell Banking
  • Embryonic Stem Cell Banking
  • Adult Stem Cell Banking
  • Dental Stem Cell Banking
  • IPS Stem Cell Banking
• Non-stem Cell Banking

On the basis of phases of banking, the global cell banking outsourcing market is segmented into:

• Cell Bank Storage
  • Master Cell Bank Storage
  • Working Cell Bank Storage
  • Cell Storage Stability Testing
• Bank Characterization and Testing
  • Safety Testing
    • Viral Cell Bank Safety Testing
    • Microbial Cell Bank Safety Testing
    • Gene Expression Testing
    • Karyology Testing
    • Gene Sequencing Testing
  • Cell Bank Preparation
    • Master Cell Bank Preparation
    • Working Cell Bank Preparation

On the basis of region, the global cell banking outsourcing market is segmented into:

• • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

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Global Cell Banking Outsourcing Market: Regional Analysis 

North America is expected to hold dominant position in the global cell banking outsourcing market during the forecast period, owing to increasing number of stem cell donations in the region. For instance, according to World Marrow Donor Association (WMDA), in 2016, the U.S. recorded over 1 million stem cell donors.

Global Cell Banking Outsourcing Market: Competitive Landscape 

Major players operating in the global cell banking outsourcing market include BioReliance Corporation, BioOutsource (Part of Sartorious Stedim Biotech Group) Ltd., Cleancells, CordLife Group Ltd., BSL Bioservice Scientific Laboratories Munich GmbH, Transcell Biologics Pvt. Ltd., Charles River Laboratories, Cryo-Cell International Inc., Wuxi Apptec, Covance, Inc., Texcell SA, Toxikon Corporation, LifeCell International Pvt. Ltd., Goodwin Biotechnology Inc., Lonza. Additionally, PX’Therapeutics SA, Reliance Life Sciences, SGS Life Sciences, Cryobanks International India, and GlobalStem Inc.

Global Cell Banking Outsourcing Market: Key Developments

• January 2018: PX’Therapeutics announced its collaboration with biotech firm, Advaxis, for process development of immunotherapies of Advaxis
• September 2017: GE Healthcare announced the introduction of Thaw CB1000, for thawing large volumes of cell therapies cryopreserved in cryo-bags majorly intended for use in research laboratory
• June 2017: Alligator Bioscience announced partnership with Sartorius Stedim Biotech Group (BioOutsource), as Cell Line Development Partner in its immuno-oncology antibody drug candidate development
• 2013: Cryo-Cell International Inc. affiliates -Saneron CCEL Therapeutics, Inc. and the University of South Florida, received patent for processing of umbilical cord blood for treatment of neurodegenerative diseases and spinal cord and brain injuries

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