Recombinant Therapeutic Antibodies and Proteins Market Share and Trend Analysis by Top Leading Players as with Revenue US$ 250 Billion till 2026
Recombinant Therapeutic Antibodies and Proteins Market
Therapeutic proteins such as non-covalent binders are developed in labs and find application in the pharmaceutical sector. Therapeutic proteins are used in the treatment of chronic and rare disorders. These proteins support a targeted therapeutic process and reimburse the lack of a pivotal protein in order to offer a tailored method of therapy. The recombinant therapeutic antibodies and proteins market is witnessing significant growth, owing to increasing approval and launch of novel products in the recent past. For instance, according to the National Center for Biotechnology Information (NCBI) data of 2017, the U.S. Food and Drug Administration (FDA) approved over 140 recombinant therapeutic proteins for human use and several hundred are currently in development. Several of these proteins are recombinant monoclonal antibodies.
The global recombinant therapeutic antibodies and proteins market size was valued at US$ 91.2 billion in 2017, and is expected to witness a robust CAGR of 12.2% over the forecast period (2018 – 2026).
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Figure 1. Global Recombinant Therapeutic Antibodies and Proteins Market Share (%), By Drug Class
Source: Coherent Market Insights Analysis (2018)
Increasing technological developments in recombinant therapeutic drugs is expected to boost growth of the market
Key players in the market are focused on combining various methodologies to develop novel recombinant therapeutic drugs. This in turn has enabled manufacturers to modify certain basic features of proteins in order to increase product quality and safety. Use of several recombinant methodologies has enhanced the half-life, functionality, and targeting ability of new therapeutic protein drugs. It has also helped to enhance the quality of products and volume. For instance, protein conjugation and derivatization methods, including albumin-fusion15, PEGylation and Fc-fusion are in trend for increasing the circulating half-life of a therapy.
Some of the widely adopted recombinant therapeutic products are monoclonal antibodies that can be produced using various platform-based approaches. This is attributed to highly specific nature of antibodies. Moreover, there are very few safety issues in human clinical trials of mAb products compared to other types of therapeutic products. Increasing R&D of monoclonal antibody drugs for novel clinical indications is also expected to boost growth of the market.
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Figure 2. Recombinant Therapeutic Antibodies and Proteins Market (US$ Bn), By Region, 2017
Source: Coherent Market Insights Analysis (2018)
Increasing government initiatives for R&D of novel recombinant therapeutic antibodies and proteins is boosting growth of the market
Major governments around the world are focused on supporting R&D in recombinant therapeutic antibodies and proteins, which is expected to boost growth of the market. For instance, in 2012, the Food and Drug Administration Safety and Innovation Act (FDASIA) was signed to provide the FDA with the capability to establish breakthrough therapy designation (BTD), a new program within the Expedited Programs for Serious Conditions. The act dealt with therapies developed for the treatment of severe disorders and which demonstrated positive clinical evidence in initial stages compared to other available therapies.
High prevalence of rare disorders is also contributing to growth of the recombinant therapeutic antibodies and proteins market. For instance, according to National institute of Health (NIH) 2018 report, an estimated 7,000 different disorders collectively affect about 10% of the U.S. population, mainly young children and many lack effective treatments. Major regulatory bodies are focused on supporting R&D of therapies for the treatment of rare disorders. For instance, in 2013, an orphan designation was given for drugs used for the treatment of less than 200,000 patients in the U.S.
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The market growth is restricted by stringent regulations that govern the performance and safety of recombinant therapeutic drugs.
Major players operating in the global recombinant therapeutic antibodies and proteins market include, Eli Lilly and Company, Abbott, F. Hoffmann-La Roche, Johnson and Johnson, Amgen Inc., Biogen Inc., Merck & Co., Sanofi S.A., Novo Nordisk, and Pfizer Inc.
Detailed Segmentation:
- Global Recombinant Therapeutic Antibodies and Proteins Market, By Drug Class:
- Plasma Protein
- Growth Factors
- Fusion Proteins
- Monoclonal Antibodies
- Hormones
- Enzyme
- Coagulation Factors
- Others
- Global Recombinant Therapeutic Antibodies and Proteins Market, By Application:
- Oncology
- Hematology
- Immunology
- Endocrinology
- Infectious Disease
- Cardiovascular Diseases
- Others
- Global Recombinant Therapeutic Antibodies and Proteins Market, By Geography:
- North America Recombinant Therapeutic Antibodies and Proteins Market
- By Drug Class:
- Plasma Protein
- Growth Factors
- Fusion Proteins
- Monoclonal Antibodies
- Hormones
- Enzyme
- Coagulation Factors
- Others
- By Application:
- Oncology
- Hematology
- Immunology
- Endocrinology
- Infectious Disease
- Cardiovascular Diseases
- Others
- By Country:
- U.S.
- Canada
- By Drug Class:
- Latin America Recombinant Therapeutic Antibodies and Proteins Market
- By Drug Class:
- By Application:
- By Country:
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- Europe Recombinant Therapeutic Antibodies and Proteins Market
- By Drug Class:
- By Application:
- By Country:
- Germany
- U.K.
- France
- Italy
- Spain
- Russia
- Rest of Europe
- Asia Pacific Recombinant Therapeutic Antibodies and Proteins Market
- By Drug Class:
- By Application:
- By Country:
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East Recombinant Therapeutic Antibodies and Proteins Market
- By Drug Class:
- By Application:
- By Country:
- GCC
- Israel
- Rest of Middle East
- Africa Recombinant Therapeutic Antibodies and Proteins Market
- By Drug Class:
- By Application:
- By Country:
- North Africa
- South Africa
- Central Africa
- North America Recombinant Therapeutic Antibodies and Proteins Market
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