CRISPR and CAS Gene Market to Garner US$ 7,603.8 Million, with a CAGR of 20.8% by 2026, Global Industry Analysis By Overview, Size, Growth, Share, Trends, Top Leaders, Regional Statistics
Global CRISPR and CAS Gene Market – Insights
CRISPR technology is a simple tool, which is used for gene editing. It is a powerful nucleic acid-targeting editing tools for genome, which allows researchers to easily alter DNA sequences and modify gene function. In this technology, protein Cas9 or CRISPR, which is an enzyme that acts as a pair of molecular scissors that is capable of cutting strands of DNA. It has many potential applications including correcting genetic defects, treating and preventing the spread of diseases, and improving crops. It is faster, cheaper, and more precise than previous techniques of editing DNA like ZFNs (Zinc Finger Nucleases) and TALENs (Transcription Activator-Like Effector Nucleases). Researchers are involved in using this technology in animal models or isolated human cells, with the aim to eventually use the technology for routinely treating diseases in humans.
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The global CRISPR and CAS gene market size was valued at US$ 1,388.1 million in 2017, and is expected to witness a CAGR of 20.8% over the forecast period (2018 – 2026).
Global CRISPR and CAS Gene Market Share (%) Analysis, By Product Type, 2017
Source: Coherent Market Insights Analysis (2019)
Growing Demand for Clinical Trials Coupled with Increasing Research & Development in CRISPR and CAS Gene therapy is expected to Drive Growth of the Global CRISPR and CAS Gene Market
Increasing research & development activities and growing demand for clinical trials for development of new technologies in CRISPR and CAS gene therapy for treatment of cancer is expected to drive growth of the global CRISPR and CAS gene market during the forecast period. For instance, The Parker Institute for Cancer Immunotherapy, a non-profit organization formed in April 2016, with a US$ 250 million grant from the Parker Foundation, agreed to sponsor the first in-human clinical trials of CRISPR-enabled technology targeting three types of cancer. The trial, led by the University of Pennsylvania, will use CRISPR-modified T-cells, a part of the human immune system, to treat myeloma, melanoma, and sarcoma. The trial was commenced in 2017.
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Global CRISPR and CAS Gene Market – Restraints
However, issues regarding ethical and safety operations about the CRISPR and CAS gene therapy for gene editing and creating genetically modified (GM) food or organism is expected to restrain growth of the market during the forecast period. For instance, in 2015, the US Food and Drug Administration (FDA) prohibited funding bills considering application of CRISPR and CAS gene technology to create IVF children from embryos that have been genetically modified.
Global CRISPR and CAS Gene Market – Regional Insights
On the basis of region, the global CRISPR and CAS Gene market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Among these regions, North America is expected to hold a dominant position in the global CRISPR and CAS Gene market during the forecast period. This is owing to regulatory approvals by authorities such as Food and Drug Administration (FDA) for clinical trial. For instance, in October 2018, CRISPR Therapeutics and Vertex Pharmaceuticals’ highly anticipated gene-editing trial, which was allowed for the first time to discover, develop, and commercialize new breakthrough therapeutics to cure blood disorders and congenital heart disease using the CRISPR/Cas9 technology in the U.S. In January 2019, CRISPR Therapeutics and Vertex Pharmaceuticals’ have been granted Fast Track Designation to CTX001 for the treatment of sickle cell disease (SCD) by FDA. CTX001 is an investigational, autologous, gene-edited hematopoietic stem cell therapy for patients suffering from severe hemoglobinopathies.
Furthermore, Asia Pacific is expected to register significant growth in the global CRISPR and CAS Gene market during the forecast period. This growth is attributed to rise in the demand of CRISPR and CAS gene therapy, especially in research and development activities. For instance, in May 2018 researchers at Kobe University in Japan successfully destroyed and deleted the regulatory genes of HIV-1 using the genome editing system CRISPR/Cas9, thereby successfully blocking the production of HIV-1 by infected cells.
Global CRISPR and CAS Gene Market Value (US$ Mn) & Y-o-Y Growth (%), 2016-2026
Source: Coherent Market Insights Analysis (2019)
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Global CRISPR and CAS Gene Market – Competitive Landscape
Key players operating in the global CRISPR and CAS Gene market are Caribou Biosciences Inc., CRISPR Therapeutics, Mirus Bio LLC, Editas Medicine, Takara Bio Inc., Synthego, Thermo Fisher Scientific, Inc., GenScript, Addgene, Merck KGaA (Sigma-Aldrich), Integrated DNA Technologies, Inc., Transposagen Biopharmaceuticals, Inc., OriGene Technologies, Inc., New England Biolabs, Dharmacon, Cellecta, Inc., Agilent Technologies, and Applied StemCell, Inc.
Detailed Segmentation:
- Global CRISPR and CAS Gene Market, By Product Type:
- Vector-based Cas
- DNA-free Cas
- Global CRISPR and CAS Gene Market, By Application:
- Genome Engineering
- Disease models
- Functional Genomics
- Knockdown/activation
- Other Applications
- Global CRISPR and CAS Gene Market, By End User:
- Biotechnology and Pharmaceutical Companies
- Academic & Government Research Institutes
- Contract Research Organizations
- Global CRISPR and CAS Gene Market, By Region:
- North America
- By Country:
- U.S.
- Canada
- By Product Type:
- Vector-based Cas
- DNA-free Cas
- By Application:
- Genome Engineering
- Disease models
- Functional Genomics
- Knockdown/activation
- Other Applications
- By End User:
- Biotechnology and Pharmaceutical Companies
- Academic and Government Research Institutes
- Contract Research Organizations
- By Country:
- Europe
- By Country:
- U.K.
- Germany
- Italy
- Spain
- France
- Russia
- Rest of Europe
- By Product Type:
- By Application:
- By End User:
- By Country:
- Asia Pacific
- By Country:
- Australia
- India
- China
- Japan
- ASEAN
- South Korea
- Rest of Asia Pacific
- By Product Type:
- By Application:
- By End User:
- By Country:
- Latin America
- By Country:
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- By Product Type:
- By Application:
- By End User:
- By Country:
- Middle East
- By Country:
- GCC
- Israel
- Rest of Middle East
- By Product Type:
- By Application:
- By End User:
- By Country:
- Africa
- By Country:
- South Africa
- Central Africa
- North Africa
- By Product Type:
- By Application:
- By End User:
- By Country:
- North America
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