Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Product Specifications, Growth Analysis, Industry Share, Global Opportunity, Regional Share, Technology Enhancements and Trends Till – 2026

Global Lysosomal Acid Lipase (LAL) Deficiency Market

Lysosomal acid lipase (LAL) deficiency is a rare inherited condition in which the body is not able to produce enough amounts of the lysosomal acid lipase (LAL) enzyme – an essential enzyme for the breakdown of fatty materials, namely cholesteryl esters and triglycerides. This usually results in the build-up of a huge amount of fatty materials in several body organs, including spleen, liver, and the gut. The deficiency of LAL leads to autosomal recessive disorders, two of which are Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). Thus, the LAL deficiency is caused due to genetic mutation in LIPA gene, which causes the loss of the LAL enzyme.

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Global Lysosomal Acid Lipase (LAL) Deficiency Market Taxonomy

On the basis of disease type,

•   Wolman Disease
• Cholesteryl Ester Storage Disease (CESD)    

Based on treatment type,

• Liver Transplant
• Hematopoietic Stem Cell Transplant

By end-users,

• Hospital
• Clinics

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FDA approval of innovative drugs is expected to fuel the growth of Lysosomal Acid Lipase (LAL) Deficiency Market

The approval of innovative drugs by the Food and Drug Administration (FDA) is expected to augment the growth of the global lysosomal acid lipase deficiency market. For instance, in 2015 the U.S. FDA approved Alexion Pharmaceutical’s Kanuma (sebelipase alfa), an innovative enzyme replacement therapy (ERT). Kanuma is the first approved therapy that reaches the underlying cause of the disease. It is the only suitable therapy for the LAL deficiency treatment. According to the National Institute for Health and Care Excellence (NICE) 2016, around 50% of patients suffering from the LAL deficiency were found to be highly susceptible to liver complications, such as cirrhosis or fibrosis.  . The increasing incidence of liver complications arising from LAL deficiency is expected to augment the demand for liver transplant, which would, in turn, fuel the global market development over the forecast period. In contrast, high costs and lack of awareness about diagnosis and treatment among people act as major restraints for the global market growth.

North America is expected to dominate market due to rapid novel innovations

Global market for the Lysosomal Acid Lipase (LAL) deficiency treatment market by Coherent Market Insights is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to dominate the lysosomal acid lipase (LAL) deficiency treatment market attributed to rapid novel innovations, drug development, and research. In 2015, FDA approved genetically modified organisms (GMO) chickens, for the production of a recombinant human lysosomal acid lipase (LAL) protein in their eggs for the treatment of lysosomal acid lipase (LAL) deficiency among Americans. Europe is expected to be the second largest region for LAL deficiency treatment market. The Europe commission in 2015 granted marketing permission of Kanuma, for the treatment of LAL deficiency for patients of all ages, which is expected to fuel the growth of Kanuma in the region.

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Global Lysosomal Acid Lipase (LAL) Deficiency Market – Key Players

The major players operating in the global lysosomal acid lipase (LAL) deficiency market include Alexion Pharmaceutical Inc., Merck & Co., Inc., Pfizer, Inc., and AstraZeneca Plc., and Teva Pharmaceutical Industries.

Table of Content

Global Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Research Report
Section 1: Global Lysosomal Acid Lipase (LAL) Deficiency Treatment Industry Overview
Section 2: Global Economic Impact on Lysosomal Acid Lipase (LAL) Deficiency Treatment Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Forecast

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