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24-Mar-2021

High Potency Active Pharmaceutical Ingredients Market Will Grow At 9.9% CAGR, To Be Valued At US$ 40,983.8 Mn By 2027, Owing To Increasing Launch Of Antibody Drug Conjugates

SEATTLE, March 24, 2021, (PHARMIWEB) — Global High Potency Active Pharmaceutical Ingredients Market – Insights

High potency active pharmaceutical ingredients (HPAPIs) are small-molecule, biologic, or hybrids of antibody–drug conjugates, which link a cytotoxic small-molecule to a monoclonal antibody. HPAPIs are used in the treatment of cancer, diabetes, and heart diseases, as they can accurately target diseased cells.

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Global High Potency Active Pharmaceutical Ingredients Market: Drivers

High prevalence of cancer is expected to propel growth of the global high potency active pharmaceutical ingredients market over the forecast period. For instance, according to the International Agency for Research on Cancer (IARC), in 2012, 14.1 million new cancer cases and 8.2 million cancer deaths were recorded worldwide. Moreover, cancer is expected to lead to 21.7 million new cases and 13 million deaths by 2030.

Moreover, growing demand for Antibody Drug Conjugates (ADC) is also expected to boost growth of the market.  HPAPIs are increasingly used in the form of ADCs. According to IMS Institute of Healthcare Informatics, 2016, 586 drugs are under development for oncology treatment, with over 70 new cancer treatments (for over 20 tumor types), entering the market over the past five years (2010-2015).

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Global High Potency Active Pharmaceutical Ingredients Market: Restraints 

However, high capital costs associated with the specialized containment technology required to protect both employees and the environment is expected to hamper growth of the global high potency active pharmaceutical ingredients market. Lack of harmonization in GMP regulations preventing cross contamination in some countries is also expected to hinder growth of the market.

Global High Potency Active Pharmaceutical Ingredients Market: Opportunities 

Increasing outsourcing of HPAPIs to contract manufacturers is expected to offer lucrative growth opportunities for players in the market. Major pharmaceutical companies are focusing on expansion of their product line in HPAPIs or outsourcing the manufacturing of HPAPIs to contract manufacturers. The outsourcing of HPAPIs manufacturing is increasing in India, China, and Eastern European countries due to low cost of manufacturing as compared to North America and Western Europe regions. For instance, in October 2017, Piramal Pharma Solutions (PPS), a contract development and manufacturing organization, invested US$ 55 million across its sites in Asia, to expand its API manufacturing capabilities and capacities. Furthermore, companies such as Evonik and Lonza are actively involved in providing contract manufacturing services to other companies.

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Global High Potency Active Pharmaceutical Ingredients Market Taxonomy

By Synthesis Route

  • Synthetic
  • Biotech

By Drug Type

  • Branded HPAPI
  • Generic HPAPI

By Manufacturer Type

  • In-House
  • Contract Research Manufacturers

By Therapeutic Applications

  • Oncology
  • Hormonal Disorders
  • Glaucoma
  • Others

By Region

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

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Global High Potency Active Pharmaceutical Ingredients Market: Regional Analysis

North America is expected to hold dominant position in the global high potency active pharmaceutical ingredients market, followed by Europe. This is owing to increasing incidence of cancer in the region. For instance, according to the American Cancer Society, 2017, 1,688,780 people are estimated to be diagnosed with cancer and 600,920 cancer deaths are estimated to occur in the US. Moreover, increasing geriatric population is also expected to boost growth of the market in North America.  For instance, according to the U.S. census bureau, 2014, 46.2 million people aged 65 years and above accounted for 14.5% of the total population in the U.S. Moreover, the number is projected to reach 98.2 million by 2060.

The market in Asia Pacific is driven by growing API manufacturing sector in countries such as China and India due to presence of low cost manufacturing facilities.

Global High Potency Active Pharmaceutical Ingredients Market: Competitive Landscape 

Major players operating in the global high potency active pharmaceutical ingredients market include, Lonza, Novartis International AG, BASF AG, Carbogen Amcis AG, Eli Lilly and Company, Teva Pharmaceutical Industries Ltd Bristol-Myers Squibb, Pfizer Inc., Roche Diagnostics., Boehringer Ingelheim, Covidien Plc, Merck & Co, Bayer AG, Sigma-Aldrich Corporation, and Sanofi Aventis.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Molecule Type
      • Market Snippet, By Production Technology
      • Market Snippet, By Application
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Key Developments
    • Regulatory Scenario
    • PEST Analysis
    • COVID-19 Impact Analysis
  4. Global High Potency Active Pharmaceutical Ingredients Market, By Molecule Type, 2016 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • Innovative
    • Generic
  5. Global High Potency Active Pharmaceutical Ingredients Market, By Production Technology, 2016 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • Chemical Synthesis
    • Biotechnology
  6. Global High Potency Active Pharmaceutical Ingredients Market, By Application, 2016 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • Oncology
    • Hormonal
    • Glaucoma
    • Others
  7. Global High Potency Active Pharmaceutical Ingredients Market, By Regions, 2016 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • North America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • U.S.
        • Canada
    • Europe
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Middle East
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • North Africa
        • Central Africa
        • South Africa
  8. Competitive Landscape
    • Company Profiles
      • Other Players
        • Company Overview
        • Product Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact
About Us:

Coherent Market Insights is a global market intelligence and consulting organization focused on assisting our plethora of clients achieve transformational growth by helping them make critical business decisions. We are headquartered in India, having office at global financial capital in the U.S. and sales consultants in United Kingdom and Japan. Our client base includes players from across various business verticals in over 150 countries worldwide. We pride ourselves in catering to clients across the length and width of the horizon, from Fortune 500 enlisted companies, to not-for-profit organization, and startups looking to establish a foothold in the market. We excel in offering unmatched actionable market intelligence across various industry verticals, including chemicals and materials, healthcare, and food & beverages, consumer goods, packaging, semiconductors, software and services, Telecom, and Automotive. We offer syndicated market intelligence reports, customized research solutions, and consulting services.

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Last Updated: 24-Mar-2021