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12-Apr-2021

[2021] Levodopa Market by Product & Geography | Global Analysis, By, Share, Key, Company, Trends, Size, Emerging Technologies, Business Revenue and Forecast to 2026

SEATTLE, April 12, 2021, (PHARMIWEB) — Global Levodopa Market – Insights

Levodopa (l-DOPA), also known as levodopa and l-3,4-dihydroxyphenylalanine, is an amino acid that converts into dopamine in the body. It is used in the treatment of neurological disorders. Carbidopa in combination with levodopa slows down the metabolism of dopamine.

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Global Levodopa Market: Drivers

R&D drugs containing levodopa is are expected to boost growth of the global levodopa market over the forecast period. For instance, Intec Pharma Ltd. is conducting clinical phase III trial for gastric retentive Accordion Pill, an immediate drug release formulation. The study is expected to be complete in September 2018. Accordion Pill is a Carbidopa/Levodopa (AP-CD/LD) combinational oral drug delivery system uses gastric retention and specific release mechanism to enhance the efficacy and safety of existing CD/LD drugs. Similarly, Impel NeuroPharma Inc. is conducting phase II clinical study for INP103, a drug-device combination product containing L-dopa and device component I231 Precision Olfactory Delivery (POD) device. The study is expected to complete in November 2018.

R&D in diagnosis of Parkinson’s disease is expected to fuel growth of the global levodopa market. For instance, Washington University School of Medicine is conducting a clinical study to measure the progression of Parkinson’s disease through controlled dose of levodopa. The study is currently in clinical phase I and is expected to complete in February 2019.

Global Levodopa Market: Restraints

Shortage of drug supply is expected to hinder growth of the global levodopa market. For instance, in September 2018, Merck Sharp & Dohme Ireland (Human Health) Ltd.  projected stock shortage of some Sinemet (Carbidopa/ Levodopa) products in the Irish market in near future due to global manufacturing delays in production and demand for resupply of these products.

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Global Levodopa Market: Regional Analysis

North America is expected to hold dominant position in the global levodopa market over the forecast period. This is attributed to approval and launch of new products. For instance, in 2015, AbbVie Inc. received the U.S. FDA approval for an extended-release oral formulation of Levodopa/Carbidopa called Duopa.

The market in Europe is driven by increasing product development activities. For instance, in March 2018, Acorda Therapeutics, Inc. submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for INBRIJA, an investigational inhaled levodopa treatment for symptoms of OFF periods (OFF symptoms implies recurrence of symptoms such as rigidity, and tremors after long period of levodopa use) in people with Parkinson’s disease taking a Carbidopa/Levodopa regimen. Similarly, in November 2015, Impax Laboratories, Inc. received European Commission (EC) marketing authorization for NUMIENT (Levodopa and Carbidopa), a modified-release oral capsule formulation for the symptomatic treatment of adult patients with Parkinson’s disease in Europe.

Global Levodopa Market: Competitive Landscape 

Major players operating in the global levodopa market include Taj Pharmaceuticals Limited., Guangzhou HanFang Pharmaceutical Company Limited, Poulvet.com, Teva Pharmaceutical Industries Ltd., UBM, Zhejiang Wild Wind Pharmaceutical Co., Ltd., and SWAPNROOP.

Global Levodopa Market – Taxonomy

By Application

  • Parkinson’s Disease
  • Dopamine Responsive Dystonia

By Drug Type

  • Rytary
  • Duopa
  • Sinemet
  • Caramet
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East
  • Africa
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Last Updated: 12-Apr-2021