Creative Proteomics Expands Service Offering With the Launch of Structure Activity Relationship (SAR) Analysis Service

Creative Proteomics, an integrated CRO company committed to providing a full range of services to support various proteome-related research projects, from the identification of single proteins to large-scale proteomic studies, has recently launched fully-developed Structure Activity Relationship (SAR) Analysis Service. SAR technology now fulfills expanding roles in handling large and expanding sources of data.

Structure Activity Relationship techniques are currently employed in a wide range of applications, including: in-silico design of virtual chemical libraries that explore molecular diversity for subsequent synthesis and screening; screening proprietary, commercially available, and public databases for lead discovery; and mining gene expression data from microarray experiments for target identification.

SAR analysis can detect functional groups that have biological effects on an organism, which facilitates the modification of biologically active compounds by changing their chemical structure. Chemists use advanced chemical synthesis techniques to introduce new chemical groups into biomedical compounds and test the effect of modifications on the biological function of the compounds. It can also be modified to establish a mathematical relationship between chemical structure and biological activity, known as quantitative structure-activity relationship (QSAR). The basic assumption of SAR analysis is that similar molecules have the same function. Therefore, the underlying question is how to define small differences at the molecular level, since each activity (e.g., reactivity, solubility, target activity) may also be associated with another difference.

“Medicinal chemistry is the core component of drug research and development. Creative Proteomics brings together top talents with rich experience from major biopharmaceutical companies in the world, and is committed to providing customers with first-class SAR structure-activity relationship modification services. Our state-of-the-art equipment and strong research capabilities can provide our clients with comprehensive services ranging from SAR-driven identification of active compounds, structure optimization, to preclinical drug candidate screening,” said the senior scientist of Creative Proteomics.

“Creative Proteomics has great advantages in medicinal chemistry, because we not only have rich experience in SAR research, but also have a mature biological team to provide data support, so that our medicinal chemistry can achieve high levels of synthesis and optimization of compounds. Based on efficient customer service, we will strive to build a new service company worthy of customers' trust,” he added.

About Creative Proteomics

Creative Proteomics, as an experienced proteomics, metabolomics, and bioinformatics services supplier, has been well equipped with advanced technologies in order to meet the increasing needs of scientists in their proteomics and metabolomics-related research.

Contact:

Address: Shirley, NY 11967, USA

Email: contact@creative-proteomics.com