Immutep announces abstracts accepted for presentation at the Society for Immunotherapy of Cancer (SITC) 2022 Annual Meeting

Immutep announces abstracts accepted for presentation at the Society for Immunotherapy of Cancer (SITC) 2022 Annual Meeting

Initial data from INSIGHT-003 trial treating patients with various solid tumours with triple combination therapy of efti, anti-PD-1 therapy, and chemotherapy to be discussed at SITC

Sydney, Australia, October 5, 2022 - Immutep Limited (ASX: IMM; NASDAQ: IMMP) (“Immutep” or “the Company”), a clinical-stage biotechnology company developing novel immunotherapies for cancer and autoimmune disease, will announce first interim data from the INSIGHT-003 clinical trial in a poster presentation at the Society for Immunotherapy of Cancer (SITC) Annual Meeting 2022, which is taking place in person in Boston, US and virtually from 8 to 12 November 2022. A Trial in Progress poster on the phase IIb TACTI-003 trial will also be presented.

The phase I INSIGHT-003 trial is the first trial evaluating Immutep’s lead product candidate, eftilagimod alpha (“efti” or “IMP321”) as part of a triple combination therapy consisting of efti and an approved standard of care combination of chemotherapy and an anti-PD-1 therapy. The trial is recruiting up to 20 patients with various solid tumours, focusing on NSCLC adenocarcinomas.

INSIGHT-003 Abstract

Title: Feasibility of eftilagimod alpha (soluble LAG-3 protein) combined with standard-of-care-therapy in advanced non-small-cell lung cancer (NSCLC) adenocarcinomas. Initial results from INSIGHT 003

Poster display session: Friday, Nov 11, 2022; 9 am – 9 pm EST

Presenter: Dr. Akin Atmaca

TACTI-003 Trial in Progress Abstract

Title: TACTI-003: A randomized Phase IIb study of eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab as first-line treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma

Poster display session: Thursday, November 10, 2022; 9 am – 8:30 pm EST

Presenter: Dr. Irene Brana

Immutep also has a Late Breaking Abstract accepted at SITC 2022. Titles for Late Breaking Abstracts will become publicly available on 2 November 2022.