SOTIO to Present the AURELIO-04 Phase 2 Study Design and Findings from BOXR Research at the SITC Annual Meeting

BASEL, Switzerland and CAMBRIDGE, Mass., October 18, 2022 / B3C newswire / -- SOTIO Biotech, a clinical stage immuno-oncology company owned by PPF Group, announced today that it will share two poster presentations, namely the Phase 2 AURELIO-04 study design of the IL-15 superagonist, SOT101 as a Trial in Progress and nonclinical data on mechanism of action of its BOXR T cell platform, at the upcoming Society for Immunotherapy of Cancer (SITC) 37^th Annual Meeting, taking place in Boston, Massachusetts from November 8-12, 2022.

The study design of AURELIO-04 will be presented by Aurélien Marabelle, M.D., Ph.D., immuno-oncologist from the Drug Development Department at Gustave Roussy Cancer Center. Findings from the study of BOXR1030 will be delivered by Pratirodh Koirala, Ph.D. and John Hinds, Ph.D., translational scientists at SOTIO Biotech Inc. (U.S.).

Poster Presentations Details:

Title: AURELIO-04: A phase 2, open-label, single-arm, multicenter study to determine the efficacy and safety of SOT101 in combination with pembrolizumab in patients with selected advanced solid tumors
Presenting Author: Aurélien Marabelle, M.D., Ph.D.,
Abstract Number: 716
Location: Poster Hall
Session Date: Thursday, November 10 – Friday, November 11
Session Time: 9:00 a.m. – 9:00 p.m. ET

Title: Exogenous GOT2 in CAR-T cells improves metabolic function and preserves early memory T cell subsets
Presenting Authors: Pratirodh Koirala, Ph.D. and John Hinds, Ph.D.
Abstract Number: 238
Location: Poster Hall
Session Date: Thursday, November 10 – Friday, November 11
Session Time: 9:00 a.m. – 9:00 p.m. ET

Selected presentation materials will be made available on the SOTIO Biotech website once the presentations conclude.

About SOTIO Biotech
SOTIO Biotech is shaping the future of cancer immunotherapies by translating compelling science into patient benefit. The robust SOTIO clinical pipeline includes a differentiated superagonist of the attractive immuno-oncology target IL-15, SOT101, currently being tested in phase II clinical trials. SOT102, a next generation Claudin18.2-targeted antibody-drug conjugate (ADC) has recently entered the clinical phase. BOXR1030, a GPC3-targeted CAR-T based on proprietary technology designed to improve on the efficacy of CAR-T therapies in the tumor microenvironment, will enter the clinical phase in 2022. SOTIO is a member of the PPF Group.
SOTIO is a registered trademark of SOTIO Biotech a.s. in selected countries.

Contacts

SOTIO Biotech 
Richard Kapsa
Head of Communication
T: (+420) 224 174 448
M: (+420) 603 280 971
kapsa@sotio.com

Media contact

LifeSci Communications
Michael Tattory
(+1) 609-802-6265
mtattory@lifescicomms.com     

Keywords: Humans; Clinical Trials, Phase II as Topic; Medical Oncology; IL15 protein, human; Interleukin-15; Receptors, Interleukin-15; T-Lymphocytes; Immunoconjugates; Neoplasms; pembrolizumab; Immunotherapy; Drug Development; Industry; Biotechnology; Switzerland

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