3D Cell Culture Market Growth; Analyzing Challenges and Opportunities and Industrial Needs

The global market of 3D cell culture was nearly $970 million in 2021 and is expected to reach $2.4 billion by 2027 with a CAGR of 13.7%. 3D cell culture is a cultural environment that empowers cells to grow and interrelate with the surrounding extracellular framework in all the three dimensions unlike traditional 2D cell culture in which the cells are grown in a flat single-layer on a plate.

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3D cell culture Market Insights

• By 2027, China's 3D culture market will be almost $161 million as it is growing at a CAGR of 14.8%, whereas Japan and Canada are forecasted to grow at 12.3% CAGR and 11.9% CAGR.
• A worldwide microfluidic segment to grow at 15.2% CAGR in which the most important countries driving this segment will be the USA, Japan, China, and Canada.
• Each year 15 million people suffer a stroke. Nearly 5 million die, and 5 million of them become disabled. In the US alone, 24% of adults, which is 58.5 million people have arthritis, with the annual medical cost and lost earnings of disabled people being almost $303.5 billion. These diseases will drive market growth as 3D cell culture is used in regenerative medicine.

Regenerative medicine in 2021 generated $22.7 billion in investment from big Pharma companies. Cell-based companies nabbed $10.1 billion, and cell therapy raised $2 billion. Most of the cash came from venture capital which invested almost $9.8 billion, a 75% increase from last year.

3D Cell Culture Market Dynamics

The main reason for adopting 3D cell culture is that it's the most suitable way to represent human tissue outside the body. 2D cell culture works in 2 dimensions, and this is not how cells grow or how they get affected by disease and injury. Stem cells growing in 3D display a more differentiation potential. Drug experiments produce efficient results, and it is comparatively easier to perform in 3D cultures reducing the time expenditure in drug discovery by pharmaceutical companies. 3D cell culture models yield good and more reliable research as the cell-to-cell and cell-to-matrix interaction is always maintained. 3D cell cultures are now grown on scaffolds allowing the cells to follow their genetics to self-organize and form 3D structures mimicking the growth inside a body. Using human cells, researchers can make tiny versions of human tissues by following this method which will be used in therapy responses and Vivo mechanisms. 3D culture can even improve input in bone cancer pathology. Due to these advancements, 3D culture demand is huge, and its market potential is going off the roof as an investment is coming from all directions. Technological advancement plays a major role and will benefit people suffering from chronic diseases like cancer, stroke, etc. The government is backing these technological advancements by providing incentives to private companies who are the flag bearer in this department, and even government-held research organizations are working in this field to innovate and discover new potential.

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3D Cell Culture Market: A thorough Segmentation Analysis

The worldwide 3D cell Culture Market is segmented based on application, end-user, and region

• 3D Cell Culture Market, by application
• Tissue engineering & Regenerative Medicine
• Stem Cell Research and Cancer
• Drug Discovery & Toxicology Testing

• 3D Cell Culture Market, by End-User
• Research Institutes
• Pharmaceutical and Biotechnology Companies
• Cosmetics Industry
• Other Users

• 3D Cell Culture Market by Region
• North America
• Mexico
• Canada
• United States

• Europe
• United Kingdom
• Italy
• France
• Germany
• Turkey
• Belgium
• Netherlands
• Switzerland
• Spain
• Russia
• Netherlands
• Rest of Europe

• Asia Pacific
• India
• Japan
• China
• Australia
• Malaysia
• Thailand
• Indonesia
• Philippines
• South Korea
• Rest of Asia Pacific

• LAMEA
• Argentina
• Brazil
• Saudi Arabia
• Uruguay
• Rest of LAMEA

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By application in 2022, regenerative medicine holds the largest portion of 3D cell culture, and investment in this field is on the rise. University of Colorado Anschutz Medical campus is investing $200 million per year for the next five years in developing regenerative medicine and cellular and gene therapies for various chronic diseases. By 2030 regenerative medicine will boost, with a worth of nearly $83 billion with a CAGR of 23.4%. In 2022, Organelle Regenerative medicine, Inc. received $4 million in funding for clinical trials and has agreed to make management changes. Stem cells and cancer are also slowly catching up with the market, and investments in these fields are taking place rapidly. Precision bioscience, a USA-based company, will receive $75 million upfront and, over time, will receive nearly $1.4 billion from Novartis for developing ARCUS-based ex vivo allogeneic CAR T and in vivo gene editing therapies.

Geographically, North America is leading in this field because of many life science companies originating from here, and technological advancement gives them the upper hand. 88% of regenerative medicine research investment comes from the National Institute of Health (NIH), the main agency for the US responsible for public health and biomedical research. This is followed by Europe, which is also investing huge sums of money in the field of 3d cell culture, which is related to regenerative medicine, stem cell research, and drug discovery. The European market is predicted to grow at nearly 8% CAGR from 2022-2030. The reason is the growing geriatric population and lifestyle changes in rich people of Europe, which are causing them chronic diseases, laying the burden on research and development.

3D Cell Culture, based on Companies

• 3D Biotic LLC
• Dickinson And Company
• Avantor, Inc.
• Advanced Biomatrix, Inc.
• Corning Incorporated, Insphero AG
• Thermo Fisher Scientific Inc.
• Lonza Group Ltd.

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