Enzyre closes Series A financing round of EUR 12M to advance pioneering diagnostic technology platform for hemophilia patients

• Funds will be used to accelerate development of proprietary ambulant diagnostic platform and establish manufacturing capabilities
• Plans to expand platform beyond hemophilia A

02 November 2022, Nijmegen, Netherlands: Enzyre, which is developing breakthrough ambulant diagnostic technology for blood coagulation testing, today announced that it has successfully raised EUR 12 million in a Series A financing led by new investor, Oost NL, with participation from i&i Biotech Fund, Demcon Investment as technology partner and existing investors, Takeda Ventures and Novalis Biotech. Part of the funding is an Innovation Credit from the Dutch Government.

The proceeds from the financing will enable Enzyre to further develop its unique diagnostic technology platform, EnzyPad, which will enable hemophilia patients to determine and monitor their coagulation status from home in real-time. The funds will support clinical trial registrations, the establishment of a sustainable manufacturing line and investment in expanding applications in the critical care setting. 

Enzyre’s first product, Hemophilia EnzyCard, uses the Company’s proprietary EnzyPad platform technology to determine the coagulation status of patients with hemophilia, a rare genetic disorder that is estimated to affect over 800,000 people worldwide.[i] Those with hemophilia A lack sufficient blood-clotting factor VIII (FVIII) activity, causing them to bleed for longer after an injury compared to healthy subjects. Due to the complexities associated with managing the condition, patients benefit from being able to safely monitor their condition at home while potentially staying connected with their care team by telemedicine. Enzyre’s technology will enable patients to self-test in a home setting, and eventually transfer their coagulation status to their treating physician through a mobile phone app and a cloud-based application. This will allow for timely personalized therapy adjustments that may improve clinical outcomes while avoiding unnecessary travel and hospital exposure, ultimately decreasing overall treatment burden and cost for patients and healthcare systems.                                                                                                     

Guido Maertens, Chief Executive Officer of Enzyre, said: “We are delighted to have closed this successful financing round which validates our technology and will underpin our ongoing development as we take Enzyre forward into the next phase of growth. We value Takeda’s continued support and welcome the commitment from a strong cohort of new and existing investors. Together we look forward to improving the quality of life for patients living with bleeding disorders by driving forward our goal to transform their standard of care.”

Pieter Rhemrev, senior investment manager at Oost NL, acting as lead investor of the syndicate, commented: “We are excited to be working with Enzyre in developing a truly innovative technology that is a potential game changer in the management of Hemophilia A and other bleeding disorders. Patient outcomes and quality of life will be dramatically improved by the ability of physicians to monitor coagulation status in real-time and we see great potential for the product to enhance personalized care. We look forward to joining this talented team and our syndicate partners in supporting Enzyre’s pathway to future success.”

[i] World Federation of Hemophilia. Report on the Annual Global Survey 2020. October 2021. https://bit.ly/3DaJhUk