PrecisionLife to Evaluate Precision Medicine Potential of Sosei Heptares Neuroscience GPCR Target

Oxford, UK, 8 November 2022 –global techbio company PrecisionLife, pioneers in precision medicine for chronic diseases, will assess the precision medicine potential of a neuroscience target nominated by Sosei Heptares, an international biopharmaceutical group specialising in structure-based drug design targeting G protein-coupled receptors (GPCRs).

Sosei Heptares will leverage the extensive insights held in PrecisionLife’s DiseaseBank™- a repository of over 40 chronic disease studies - to determine the precision medicine opportunity of a drug targeting the nominated GPCR. The project aims to augment Sosei Heptares’ knowledge of the designated GPCR target with genetic support and prevalence insights in patients.

PrecisionLife’s studies examine differences in the chosen target, and in the biological systems on which it acts, between patients and healthy individuals. The approach taken by PrecisionLife has the potential to identify individuals who are more likely to respond to therapeutics acting on the biological target. This knowledge is anticipated to inform focused translational medicine studies and ensure that the right patients are included in future clinical trials.

Alastair Brown, Senior VP Translational Medicine, Sosei Heptares, commented: “We are excited to build on our translational medicine strategy, which sees us partnering with leading-edge companies to find innovative ways to leverage our world leading discovery and early development capabilities. We look forward to working with PrecisionLife to drive our understanding of chronic disease biology and patient stratification, which is a key area of focus for Sosei Heptares.”

Dr Steve Gardner, CEO, PrecisionLife, added: “We're delighted to initiate this exciting project with Sosei Heptares, applying our unique combinatorial approach to enhance the biological validation, facilitate translation, and optimize clinical trial design in the treatment of CNS diseases. This is an area in which we share a deep commitment and complementary expertise, so we're thrilled to welcome Sosei Heptares as the newest biopharma company we're supporting to develop better, more personalized treatment options for unmet medical needs.”