DNA Methylation Market to achieve CAGR of 15% from 2023 to 2032, owing to increasing cases of cancer globally | insightSLICE
The global DNA Methylation market size was estimated to be US$ 1.25 billion in 2021 and is expected grow at a CAGR of 15% between 2023 to 2032.
DNA methylation is a heritable epigenetic marker that occurs when certain enzymes called DNA methyltransferases covalently transfer a methyl group to the C-5 position of the DNA cytosine ring (DNMTs). In the human genome, DNA methylation typically takes place in cytosines. In somatic cells, a CpG dinucleotide context is where more than 98% of DNA methylation occurs.
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The process of adding or removing a methyl group (-CH3) from a DNA strand is known as DNA methylation. Without altering the sequence, the insertion of the methyl group aids in modifying or changing the activity of the DNA segment. A methyl group at the edge of a gene promoter will inhibit transcription. Gene editing uses DNA methylation to control X chromosome inactivation and tissue-specific gene expression.
The key players of the Global DNA Methylation Market are:
Some of the key players in the market are Thermo-Fisher Scientific Inc., Agilent Technologies Inc., BioRad Laboratories Inc., Exact Sciences Corporation, QIAGEN N.V., Active Motif, Inc., Illumina Inc., EpiGentek Group Inc., Pacific Biosciences Inc., New England Biolabs Inc., Merck KGaA, Zymo Research Corporation, and PerkinElmer Inc.
Hence, increasing use of the technology in agri genomic studies and rising usage of DNA methylation in DNA sequencing analysis are the reasons anticipated to propel market revenue growth during the forecast period.
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Driving factors for the growth of Global DNA Methylation Market
Using the DNA methylation analysis method, researchers can identify possible biomarkers and learn a lot about regulating genes. Obesity, cancer, and other disease processes have all been linked to abnormal DNA methylation.
Additionally, it promises potential use in agronomic research to examine how crops respond to drought, high-temperature changes, and other environmental disturbances.
Furthermore, research using genome-wide methylation profiling has been made possible by several high-throughput technologies, including microarrays and next-generation sequencing (NGS). With these technologies, it is possible to comprehend the relevance of DNA methylation and the functional effects of variation.
COVID-19 impact on DNA Methylation market
Movement limitations brought on by the COVID-19 outbreak had a negative market impact since they made it difficult for laboratories and research institutions to conduct testing and research.
However, after the pandemic, the reopening of research facilities led to a rise in the use of DNA methylation. Additionally, the availability of many test kits has given market participants numerous opportunities.
Global DNA Methylation Market Key Segments:
By Technology:
- Bisulfite DNA modification
- Methylated DNA Immunoprecipitation
- High-Resolution Melt Analysis
- Others
By Application:
- DNA Sequencing
- Oncology Research
- Microarray
- Immunological Assay
- Others
By End-Use:
- Biotechnology Industry
- Pharmaceutical Industry
- Academic Institutions
- Research Laboratories
- Others
By Product:
- Enzymes
- Reagents
- Kits
- Instruments and Consumables
- Others
By Geography:
- North America
- United States
- Canada
- Rest of North America
- Europe
- Germany
- United Kingdom
- Italy
- France
- Spain
- Rest of Europe
- Asia Pacific
- Japan
The leading market segments of Global DNA Methylation Market
Consumables held the largest market share due to rising quick test usage and the desire for frequent wear-out use. Consumables are frequently used in DNA sequencing operations and diagnosis processes. An increase in consumer demand for high throughput results and quick turnaround times drives the expansion of this segment of the DNA methylation market.
The Polymerase Chain Reaction (PCR) and microarray market segments for DNA methylation are based on technology. Due to a growth in its use in diagnostics and DNA sequencing, the polymerase chain reaction category had the largest market share.
The rise in DNA methylation was sparked by increased demand for PCR technology in diagnostics and genomics. PCR technology increased dramatically in importance as a diagnostic technique during COVID-19.
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Regional performance of DNA Methylation Market
North America is predicted to provide a disproportionately larger revenue share to the global DNA methylation market during the forecast period.
DNA methylation is expected to remain in high demand due to its broad application in several sectors. The use of DNA methylation as an epigenetic biomarker has grown as a result of this fast expansion in the scientific community. The necessity for the method is anticipated to rise as a result.
The region’s dense concentration of significant actors has also improved the usage of DNA methylation methods in biotechnology. It is anticipated that these factors will encourage market revenue expansion in the region.
The Europe market is predicted to have consistent revenue CAGR development throughout the forecast period. The growing demand for the method in cancer and epigenetic research laboratories is fueling the rise of the Europe DNA methylation market.
Asia Pacific is predicted to show a constant CAGR during the projection period due to DNA methylation as a potential diagnostic tool in clinical research.
Researchers in this area developed a technique called single-cell transposable element methylation sequencing (scTEM-seq), which enables inexpensive evaluation of DNA methylation levels. This is expected to increase DNA methylation acceptability and hasten the sector’s expansion. The pharmaceutical industry’s meteoric rise is also anticipated to drive market revenue growth
Market Growth Limiting Factors:
The market can be constrained by a lack of experience conducting DNA methylation tests. Despite the promise of DNA methylation in various biotechnological applications, the relatively small pool of qualified specialists continues to be a barrier to progress.
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