Roche introduces navify® Algorithm Suite, a digital library of medical algorithms that enhances clinical decision-making to optimise patient care

Roche introduces navify® Algorithm Suite, a digital library of medical algorithms that enhances clinical decision-making to optimise patient care

·        At the global HIMSS¹ Conference, Roche showcases navify Algorithm Suite, a single platform offering clinicians access to medical algorithms generating insights to help improve care decisions.

·        navify Algorithm Suite is a secure digital ecosystem that links physicians easily to a range of medical algorithms from Roche and its innovation partners without the hurdle of integrating multiple algorithm providers.

·        First available medical algorithms focus on identifying patients at risk for some liver and colon cancers. Medical algorithms for cardiac, lung and other disease states are in the pipeline.

Rotkreuz, 11 April 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) introduces its navify® Algorithm Suite, a single platform hosting a library of digital medical algorithms that generate patient-centric insights and can aid earlier diagnosis of cancer and other conditions per intended use, at the HIMSS Global Conference in Chicago, USA, from April 17- 21, 2023. 

Physicians use medical algorithms, evidence-based decision-making tools, in the diagnosis, treatment and monitoring of patients to optimise care, increase early diagnosis and adhere to guidelines. Use of real-time clinical decision support is associated with adherence to evidence-based guidelines and as an aid in screening of colorectal cancer.^2,3

“As healthcare data is set to grow annually by 36%,⁴ digital medical algorithms can generate actionable insights which physicians can use to start delivering on the promise of personalised healthcare,” said Moritz Hartmann, Global Head of Roche Information Solutions at Roche Diagnostics. "With navify Algorithm Suite, clinicians can easily order the medical algorithms they need from Roche and other providers to get enhanced insights that improve patient care."

navify Algorithm Suite offers labs and hospitals one platform to connect easily to digital medical algorithms from a diverse range of innovators. This makes it easier for physicians to use and adopt the medical algorithms they need. Simultaneously, navify Algorithm Suite also offers universities and other providers of digital algorithms a direct channel to distribute their proven innovations to practising physicians in markets worldwide.

The platform is designed to be embedded in existing healthcare workflows and the lab or hospital information system (LIS/HIS) and/or the EHR/EMR (electronic health/medical record).  Designed for optimal information security management, navify Algorithm Suite complies with GDPR (General Data Protection Regulation) regulations in Europe as well as HIPAA (Health Insurance Portability and Accountability) in the USA.

The first algorithms in the navify Algorithm Suite focus on oncology:

·        GAAD⁵ is intended as an aid in the diagnosis of early stage Hepatocellular Carcinoma (HCC) in patients with chronic liver disease. GAAD  (an in-vitro diagnostic multivariate index assay) analyses gender, age in combination with results of two Roche assays Elecsys AFP and Elecsys PIVKA. This CE-marked algorithm⁶ may help physicians diagnose early stage hepatocellular carcinoma (HCC).  Liver cancer is the sixth most common cancer worldwide⁷ and HCC is the most common form of liver cancer accounting for ~90% of cases.⁸ It is not available in the US.

·        A pre-screening algorithm to identify at-risk healthy people for colorectal cancer. The ColonFlag algorithm from the Medial EarlySign company helps identify patients at high-risk for colon cancer by analysing age, sex, and a recent complete blood count (CBC).⁹  Colorectal cancer is the 3rd most common cancer worldwide with more than 1.9 million new cases of colorectal cancer in 2020.¹⁰ In the US, the ColonFlag algorithm is marketed as LGI-Flag™, as an indication for lower GI disorders.

Additional algorithms for oncology, cardiology and other diseases, such as lung and  infectious diseases, are already in the pipeline. navify Algorithm Suite is currently available in Europe and Asia-Pacific.

About navify

The navify portfolio includes more than 30 digital solutions¹¹ for labs, hospitals and patients worldwide. navify digital solutions securely integrate data across diverse care settings, connecting the healthcare community and accelerating clinician access to the latest innovations and medical insights. Healthcare organisations can visit navify Marketplace to browse and request a growing number of next generation digital solutions from Roche and other companies — all designed to drive operational and clinical excellence.  More information is also available at navify.com.

About Roche

Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world’s largest biotechnology company and the global leader in in-vitro diagnostics. The company pursues scientific excellence to discover and develop medicines and diagnostics for improving and saving the lives of people around the world. We are a pioneer in personalised healthcare and want to further transform how healthcare is delivered to have an even greater impact. To provide the best care for each person we partner with many stakeholders and combine our strengths in Diagnostics and Pharma with data insights from the clinical practice.

In recognising our endeavour to pursue a long-term perspective in all we do, Roche has been named one of the most sustainable companies in the pharmaceuticals industry by the Dow Jones Sustainability Indices for the thirteenth consecutive year. This distinction also reflects our efforts to improve access to healthcare together with local partners in every country we work.

Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan.

For more information, please visit www.roche.com.

All trademarks used or mentioned in this release are protected by law.

References

1. Healthcare Information and Management Systems Society (HIMSS)
2. The American Journal of Managed Care. Choosing Wisely Clinical Decision Support Adherence and Associated Inpatient Outcomes [Internet; cited 2018 Aug 15]. Available from: Choosing Wisely Clinical Decision Support Adherence and Associated Inpatient Outcomes
3. Collaboration to Improve Colorectal Cancer Screening Using Machine Learning NEJM Catalyst Innovations in Care Delivery 2022; 04 Vol. 3 No. 4 | Published March 16, 2022 - April 2022 Daniel Underberger, MD, Keith Boell, DO,MS-HQSM, SFHM,Jeremy Orr, MD, MPH, Cory Siegrist, MBA, and Sara Hunt Available from: https://catalyst.nejm.org/doi/full/10.1056/CAT.21.0170
4. Reinsel D, Gantz J, Rydning J. The Digitization of the World from Edge to Core. IDC White Paper – #US44413318. 2018 Nov.
5. Elecsys GAAD is an in vitro diagnostic multivariate index assay intended to provide a semi-quantitative result by combining in an algorithm the quantitative measurements of Elecsys AFP assay and Elecsys PIVKA‑II assay in human serum and plasma with gender and age. Elecsys GAAD is intended as an aid in diagnosis of early stage Hepatocellular Carcinoma (HCC). Elecsys GAAD is indicated for adults who meet the following criteria: diagnosis of chronic liver disease and recommended for surveillance due to increased risk of developing HCC. Elecsys GAAD must be interpreted in conjunction with other diagnostic findings and clinical information in accordance with standard clinical management guidelines.
6. GAAD is not registered in all countries, please check for local country registration.
7. World Cancer Research Fund International. Liver cancer statistics [Internet] Available from: https://www.wcrf.org/cancer-trends/liver-cancer-statistics/
8. Nature reviews disease primers. Hepatocellular carcinoma [Internet; cited 2021 Jan 21] Available from:  https://www.nature.com/articles/s41572-020-00240-3
9. NEJM Catalyst. Collaboration to Improve Colorectal Cancer Screening Using Machine Learning, Innovations in Care Delivery 2022; 04 Vol. 3 No. 4 [Internet; cited 2022 April] Available from: https://doi.org/10.1056/CAT.21.0170 and https://catalyst.nejm.org/doi/full/10.1056/CAT.21.0170 
10. World Cancer Research Fund International. Colorectal cancer statistics [Internet] Available from: https://www.wcrf.org/cancer-trends/colorectal-cancer-statistics/
11. Digital solutions today under cobas® infinity or Viewics will transition to the navify brand over time, continuing to deliver the same value to healthcare organisations.

Media contacts

Monica Ryser, Head of Communications, Lab Insights, Roche Information Solutions
+41 79 909 4099, monica.ryser@roche.com

Christine Englund, Head of Communications, Provider Insights, Roche Information Solutions

+1 669 301 8709, christine.englund@roche.com

Biography - Moritz Hartmann

Moritz Hartmann is Head of Roche Information Solution (RIS), which focuses on delivering data-driven solutions that empower healthcare professionals and patients to make insights-based decisions. Connecting the lab, care and home settings, these innovative digital solutions help unlock digital ecosystems across the care continuum for financial, operational, and clinical insights that drive personalized healthcare for patients around the globe. Moritz started his career in the tourism industry developing online travel booking engines. He joined Roche in 2005 and since, has successfully led large and diverse organizations and teams across different regions and divisions while driving innovative digitization projects and partnerships. Moritz was appointed Head of the newly created Roche Information Solutions (RIS) in May 2021. A German native, Moritz holds degrees in Controlling and Finance as well as Marketing and International Management and an MBA from the Northwestern University - Kellogg School of Management.