Downstream Processing Market is Booming and Predicted to Hit $92.0 Billion by 2030

According to the report published by Allied Market Research, the global Downstream Processing Market was estimated at $21.8 billion in 2020 and is expected to hit $92.0 billion by 2030, registering a CAGR of 13.5% from 2021 to 2030.

The study analyzes the important strategies, drivers, competition, market dynamics, size, and important investment regions.

Key Takeaways:

Downstream processing refers to the purification and separation steps that occur after the production of biological materials, such as pharmaceuticals, enzymes, vaccines, and biofuels. It involves various techniques to separate and purify the desired product from the raw material or fermentation broth.

Growth Drivers: The downstream processing market is primarily driven by the increasing demand for biopharmaceuticals, advancements in technology for efficient purification, rising prevalence of chronic diseases requiring targeted therapies, and the growing use of biotechnology in various industries.

Biopharmaceuticals Dominate: The pharmaceutical sector is a major contributor to the downstream processing market. Biopharmaceuticals, including monoclonal antibodies, recombinant proteins, and vaccines, constitute a significant portion of the products that undergo downstream processing.

Chromatography Techniques: Chromatography, including techniques like affinity chromatography, ion-exchange chromatography, and size-exclusion chromatography, is a vital part of downstream processing. These techniques help separate and purify target molecules based on their properties.

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Covid-19 scenario-

• Rise in demand for Covid-19 vaccines across the world impacted the global downstream processing market positively, since downstream process is an important method utilized for the production of vaccines.
• The key players in the industry also heightened their production to cater to the demand for products.

Market Drivers:

Increasing Demand for Biopharmaceuticals: The rising prevalence of chronic diseases and the demand for targeted therapies have led to a growing demand for biopharmaceutical products such as monoclonal antibodies, vaccines, and recombinant proteins. Downstream processing is essential for purifying and separating these complex molecules.

Advancements in Technology: Technological advancements in chromatography, filtration, and other separation techniques have significantly improved the efficiency and effectiveness of downstream processing. Newer and more sophisticated technologies enable better separation and purification of target molecules.

Market Segmentation:

Product Type:

• • Biopharmaceuticals: Includes monoclonal antibodies, vaccines, recombinant proteins, gene therapies, and cell-based therapies.
  • Nutraceuticals: Includes vitamins, dietary supplements, and functional foods.
  • Specialty Chemicals: Includes enzymes, biofuels, and industrial chemicals.

Technique:

• • Chromatography: Separation technique based on differences in molecular properties.
  • Filtration: Process of separating solids from liquids using porous materials.
  • Centrifugation: Utilizes centrifugal force to separate particles from a fluid.
  • Ultrafiltration/Diafiltration: A filtration process that removes solutes and small particles from a solution.
  • Precipitation: Formation of solids from a solution due to changes in conditions.
  • Extraction: Separation technique based on differences in solubility.
  • Others: Including crystallization, membrane separation, and adsorption.

End User:

• • Pharmaceutical and Biotechnology Companies: Major consumers of downstream processing for producing biopharmaceuticals.
  • Academic and Research Institutes: Utilized for research, process development, and training.
  • Contract Manufacturing Organizations (CMOs): Provide downstream processing services to pharmaceutical companies.
  • Food and Beverage Industry: For processing nutraceuticals and functional food ingredients.
  • Others: Including chemical industry, environmental applications, and energy sector.

Mode of Operation:

• • Batch Processing: Sequential processing of limited quantities in batches.
  • Continuous Processing: Ongoing processing without interruption for higher efficiency.
  • Semi-Continuous Processing: Combines aspects of both batch and continuous processing.

Component:

• • Filters: Including depth filters, membrane filters, and pre-filters.
  • Chromatography Columns: Used for separation and purification.
  • Centrifuges: Equipment for separating particles from liquids.
  • Evaporators: Used in concentration processes.

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Competitive Landscape:

The key market players analyzed in the global downstream processing market report include Danaher Corporation, Repligen Corporation, Thermo Fisher Scientific Inc., Merck & Co., Inc., Boehringer Ingelheim, Lonza Group AG, Eppendorf AG, 3M Company, Finesse Solutions, Inc., and Sartorius Stedim Biotech S.A. These market players have incorporated several strategies including partnership, expansion, collaboration, joint ventures, and others to brace their stand in the industry.

Regional Growth Dynamics:

Asia-Pacific witnessed the highest growth rate for the downstream processing market and is expected to continue this trend throughout the forecast period, which is attributed to rise in expenditure on healthcare and improvement in the medical and healthcare infrastructure. In addition, the key market players focus on opportunities offered by the growing demand for single-use systems in the downstream process. This system is highly cost-effective, which has gained popularity among end users. Moreover, significant growth of the pharmaceutical and biotechnology industries supplements the market growth.

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VALUE PROPOSITIONS RELATED TO THE REPORT:

• Powered with Complimentary Analyst Hours and Expert Interviews with Each Report
• Comprehensive quantitative and qualitative insights at segment and sub-segment level
• Covid 19 impact trends and perspective
• Granular insights at global/regional/country level
• Deep-rooted insights on market dynamics (drivers, restraints, opportunities) and business environment
• Blanket coverage on competitive landscape

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