Nucleic Acid Therapeutics Market Predicted to Surpass USD 12.2 billion by 2031, AMR

According to the report published by Allied Market Research, the global nucleic acid therapeutics market was estimated at $4.1 billion in 2021 and is expected to hit $12.2 billion by 2031, registering a CAGR of 11.6% from 2022 to 2031. The study analyzes the important strategies, drivers, competition, market dynamics, size, and important investment regions.

Gene Silencing and Gene Editing: Nucleic acid therapeutics can be used for gene silencing and gene editing. Gene silencing involves suppressing the expression of specific genes associated with disease, while gene editing aims to modify the DNA sequence itself. Both approaches offer potential therapeutic avenues for addressing genetic diseases.

Clinical Advancements: Several nucleic acid therapeutics have advanced into clinical trials and received regulatory approvals. For example, the first RNA interference (RNAi)-based therapeutic, Onpattro (patisiran), was approved by the U.S. Food and Drug Administration (FDA) in 2018 for the treatment of hereditary transthyretin-mediated amyloidosis.

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Market Segmentation:

Type of Nucleic Acid Therapeutics:

a. RNA-based Therapeutics: This segment includes mRNA-based therapeutics, small interfering RNA (siRNA), antisense oligonucleotides (ASOs), and microRNA-based therapeutics.
b. DNA-based Therapeutics: This segment includes gene therapy approaches utilizing plasmid DNA or viral vectors for gene delivery and expression.

Therapeutic Application:

a. Genetic Disorders: Nucleic acid therapeutics targeting genetic disorders caused by specific gene mutations or variations.
b. Cancer: Nucleic acid therapeutics used in cancer treatment, such as gene silencing, immune stimulation, or targeted gene therapy approaches.
c. Infectious Diseases: Nucleic acid-based therapies targeting viral or bacterial infections.
d. Cardiovascular Diseases: Nucleic acid therapeutics for the treatment of cardiovascular conditions, including gene-based therapies for heart failure, atherosclerosis, etc.
e. Rare Diseases: Nucleic acid therapeutics developed specifically for rare diseases with a genetic basis.

Delivery Method:

a. Lipid Nanoparticles: Nucleic acid therapeutics delivered using lipid-based nanoparticles for efficient cellular uptake and gene expression.
b. Viral Vectors: Nucleic acid therapeutics delivered using viral vectors, such as adeno-associated viruses (AAVs) or lentiviruses, for gene delivery.
c. Non-viral Vectors: Nucleic acid therapeutics delivered using non-viral vectors, such as polymer-based nanoparticles or electroporation techniques.

Geography:
a. North America
b. Europe
c. Asia Pacific
d. Latin America
e. Middle East and Africa

Stage of Development:
a. Preclinical: Therapeutics that are still in the early stages of development, including in vitro and animal studies.
b. Clinical: Therapeutics that have advanced to clinical trials, typically categorized into different phases (Phase I, Phase II, Phase III).
c. Approved: Therapeutics that have received regulatory approval for commercialization.

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Regional Growth Dynamics:

Based on region, the market across North America generated more than two-fifths of the global market revenue in 2021, and is anticipated to retain the lion’s share by 2031. The Asia-Pacific region, on the other hand, would also manifest the fastest CAGR of 13.8% during the forecast period. The other regions studied in the report include LAMEA and Europe.

Competitive Landscape:

DS Smith Plc, Evergreen Packaging LLC, International Paper, Metsä Board, Mondi Plc, Nippon Paper Industries Co. Ltd., Nampak Products Ltd., Amcor Plc, Nine Dragons Paper (Holdings), Oji Fibre Solutions (NZ) Ltd., Sappi, Stora Enso, Smurfit Kappa Group Plc., Svenska Cellulosa Aktiebolaget (SCA), Westrock, and Keystone Folding Box.

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VALUE PROPOSITIONS RELATED TO THE REPORT:

• Powered with Complimentary Analyst Hours and Expert Interviews with Each Report
• Comprehensive quantitative and qualitative insights at segment and sub-segment level
• Covid 19 impact trends and perspective
• Granular insights at global/regional/country level
• Deep-rooted insights on market dynamics (drivers, restraints, opportunities) and business environment
• Blanket coverage on competitive landscape
• Winning imperatives
• Exhaustive coverage on ‘Strategic Developments’ registered by leading players of the market

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Allied Market Research (AMR) is a full-service market research and business-consulting wing of Allied Analytics LLP based in Portland, Oregon. Allied Market Research provides global enterprises as well as medium and small businesses with unmatched quality of “Market Research Reports” and “Business Intelligence Solutions.” AMR has a targeted view to provide business insights and consulting to assist its clients to make strategic business decisions and achieve sustainable growth in their respective market domain.