Global Enzyme Replacement Therapy Industry Set to Reach US$ 13.8 Billion by 2028 with a Resilient 6.7% CAGR | Reports FMI

The Global Enzyme Replacement Therapy Industry is embarking on an extraordinary trajectory, poised to achieve a substantial revenue milestone. According to the latest analysis by Future Market Insights (FMI), the industry is projected to witness a remarkable surge from US$ 9.3 billion in 2022 to an impressive US$ 13.8 billion by the end of 2028, reflecting a robust Compound Annual Growth Rate (CAGR) of 6.7%.

These insights, gleaned from FMI’s comprehensive analysis, illuminate pivotal trends and drivers that are reshaping the global healthcare landscape. ERT, representing over 63% of the hormone replacement market globally, emerges as a cornerstone in the treatment paradigm for various uncommon disorders. The rising prevalence of these conditions underscores the critical role that enzyme replacement therapy plays, with ongoing medical research expected to further accelerate this development.

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Global Enzyme Replacement Therapy Industry: Regional Insights

With nearly 25%-30% market share, North America dominated the Global Enzyme Replacement Therapy Industry in 2017, partly due to the presence of leading market players in the region. In developing regions such as Latin America, advancements in medical facilities are helping the region cope with the healthcare crisis. Medical facilities in Brazil are equivalent to hospitals in the United States, with some even exceeding American standards. Brazil offers everything from large, full-service hospitals to smaller, intimate private clinics.

Brazil has developed into a centre of excellence for healthcare in Latin America, with major universities that support research, teaching and training of medical professionals. Western Europe is the second largest market globally and is expected to be valued at US$ 2,893.2 Mn by 2028, with France, Italy and Spain projected to witness significant growth rates. Japan is expected to be the third largest market for enzyme replacement therapy.

Global Enzyme Replacement Therapy Industry: Segmentation & Forecast

The Global Enzyme Replacement Therapy Industry has been segmented based on therapeutic condition, route of administration, distribution channel and region. Therapeutic conditions in the enzyme replacement therapy markets include Fabry disease, Gaucher disease, mucopolysaccharidosis, Pompe disease, lysosomal acid lipase deficiency and others.

Globally, the mucopolysaccharidosis therapeutic condition is the most attractive segment. The injectable segment remains the most lucrative route of administration in the Global Enzyme Replacement Therapy Industry. Among all distribution channels for enzyme replacement therapy, speciality treatment pharmacies are expected to be the most lucrative, followed by hospital pharmacies.

Key Research Findings

Enzyme replacement therapy is used in the treatment of rare diseases and the global market is projected to create incremental opportunity of US$ 6,448.3 Mn between 2022 and 2028

When compared to other established markets such as North America, the enzyme replacement therapy markets in Japan and Western Europe are expected to witness fast and steady growth, partly due to the increasing governmental support and growing demand for enzyme replacement therapy for the treatment of rare diseases.

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Global Enzyme Replacement Therapy Industry: Competitive Landscape

• Sanofi S.A. (Genzyme Corporation)
• Shire plc.
• Pfizer Inc.
• Alexion Pharmaceuticals Inc.
• BioMarin Pharmaceutical Inc.
• Ultragenyx Pharmaceutical Inc.
• Johnson & Johnson Services Inc.
• Allergan plc.
• Leadiant Biosciences Inc.

Pompe Disease Treatment Market Is a type of treatment for certain genetic diseases that are caused by a deficiency in a specific enzyme. This therapy involves administering the missing enzyme to the patient, usually through intravenous infusion.

Key Segments of Global Enzyme Replacement Therapy Industry Survey

Global Enzyme Replacement Therapy Industry by Therapeutic Condition:

• Enzyme Replacement Therapy for Fabry Disease
• Enzyme Replacement Therapy for Gaucher Disease
• Enzyme Replacement Therapy for Mucopolysaccharidosis
  • MPS I
  • MPS II (Hunter Syndrome)
  • MPS IVA (Morquio Syndrome, Type A)
  • MPS VI (Maroteaux-Lamy Syndrome)
  • MPS VII (Sly Syndrome)
• Enzyme Replacement Therapy for Pompe Disease
• Enzyme Replacement Therapy for Lysosomal Acid Lipase Deficiency
• Others

Global Enzyme Replacement Therapy Industry by Route of Administration:

• Oral Enzyme Replacement Therapy
• Injectable Enzyme Replacement Therapy

Global Enzyme Replacement Therapy Industry by Distribution Channel:

• Hospital Pharmacies
• Specialty Treatment Pharmacies
• Retail Pharmacies

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Author

Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.

Identifying key challenges clients face and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.

Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a team of over 5,000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.

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