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16-May-2024

Market Insights: Single-use Bioprocessing Industry to Grow at 17.6% CAGR Over the Next Decade

The Single-use Bioprocessing Market is poised for substantial growth, driven by multiple factors including the rising demand for biopharmaceuticals and advancements in bioprocessing technologies. The market size is expected to expand from USD 27.6 billion in 2023 to approximately USD 139.6 billion by 2033, reflecting a robust compound annual growth rate (CAGR) of 17.6% during the forecast period from 2024 to 2033.

This growth can be attributed to several key factors. The increasing adoption of single-use technologies in biopharmaceutical manufacturing, due to their cost-efficiency, flexibility, and reduced risk of contamination, is a significant driver. Additionally, the expanding biologics market, with more companies outsourcing bioproduction to contract development and manufacturing organizations (CDMOs), further boosts the demand for single-use bioprocessing systems. The flexibility and ease of scaling provided by these technologies enable quicker responses to market demands and innovation in drug development​​.

However, the market faces challenges such as the high costs of single-use components and concerns related to extractables and leachables, which can impact product safety. These issues necessitate stringent regulatory compliance and continuous innovation to mitigate risks and enhance product reliability.

Recent developments in the market include strategic acquisitions and product innovations by major players. For instance, Thermo Fisher Scientific’s launch of advanced single-use bioreactors and Sartorius Stedim Biotech’s acquisition of Danaher’s chromatography solutions highlight ongoing efforts to enhance technological capabilities and expand market presence. Additionally, increased investments in R&D, particularly in regions like Asia-Pacific, are propelling market growth by fostering innovation and expanding the use of single-use systems in new biopharmaceutical applications​.

Key Takeaways

  • The market size for single-use bioprocessing in 2023 is USD 27.6 billion, with a forecasted revenue of USD 139.6 billion by 2033, indicating a CAGR of 17.6%.
  • North America dominates the market with a 36.8% share, valued at USD 10.15 billion, showcasing strong adoption of single-use bioprocessing technologies.
  • Simple & Peripheral Elements lead the product category with over 47.2% market share, emphasizing their importance in driving industry advancements.
  • Upstream Bioprocessing holds a significant 55.9% market share, highlighting its crucial role in establishing successful bioproduction workflows.
  • Biopharmaceutical Manufacturers command a 56.9% market share, underscoring the vital role of single-use technologies in manufacturing processes.
  • North America secures a 36.8% share in the Single-use Bioprocessing Market, with a market value of USD 10.1 billion, demonstrating regional dominance.

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Single-use Bioprocessing Market Key Segments

Product

  • Simple & Peripheral Elements
    • Tubing, Filters, Connectors, & Transfer Systems
    • Bags
    • Sampling Systems
    • Probes & Sensors
      • pH Sensor
      • Oxygen Sensor
      • Pressure Sensors
      • Temperature Sensors
      • Conductivity Sensors
      • Flow Sensors
      • Others
    • Others
  • Apparatus & Plants
    • Bioreactors
    • Mixing, Storage, & Filling Systems
    • Filtration System
    • Chromatography Systems
    • Pumps
    • Others
  • Work Equipment
    • Cell Culture System
    • Syringes
    • Others

Workflow

  • Upstream Bioprocessing
  • Fermentation
  • Downstream Bioprocessing

End-use

  • Biopharmaceutical Manufacturers
  • CMOs & CROs
  • In-house Manufacturers
  • Academic & Clinical Research Institutes

Key Regions

  • North America (The US, Canada, Mexico)
  • Western Europe (Germany, France, The UK, Spain, Italy, Portugal, Ireland, Austria, Switzerland, Benelux, Nordic, Rest of Western Europe)
  • Eastern Europe (Russia, Poland, The Czech Republic, Greece, Rest of Eastern Europe)
  • APAC (China, Japan, South Korea, India, Australia & New Zealand, Indonesia, Malaysia, Philippines, Singapore, Thailand, Vietnam, Rest of APAC)
  • Latin America (Brazil, Colombia, Chile, Argentina, Costa Rica, Rest of Latin America)
  • Middle East & Africa (Algeria, Egypt, Israel, Kuwait, Nigeria, Saudi Arabia, South Africa, Turkey, United Arab Emirates, Rest of MEA)

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Key Players Analysis

Sartorius AG is a key player in the single-use bioprocessing sector, offering a wide range of products and solutions designed to enhance biopharmaceutical manufacturing. The company focuses on single-use bioreactors, filtration assemblies, and disposable mixers, which streamline bioprocessing and reduce contamination risks. Sartorius’ strategic acquisitions, such as Polyplus and Xell AG, have expanded its capabilities in cell and gene therapies. The company anticipates significant growth, driven by innovations and increased demand for biopharmaceutical products, projecting an annual sales revenue increase of over 10% through 2028​​.

Danaher Corporation, through its Cytiva division, is a leader in single-use bioprocessing technologies. Cytiva’s portfolio includes single-use bioreactors, chromatography systems, and cell culture media. These products facilitate efficient and scalable bioprocessing, essential for the production of vaccines and biologics. Danaher’s focus on innovation and acquisitions, such as the integration of Pall Corporation, has strengthened its market position. The company’s commitment to improving biomanufacturing processes is expected to drive continued growth in the sector​.

Thermo Fisher Scientific is a prominent player in the single-use bioprocessing market, offering comprehensive solutions including disposable bioreactors, media bags, and filtration systems. These products support various stages of biopharmaceutical production, enhancing efficiency and reducing contamination risks. Thermo Fisher’s extensive R&D efforts and strategic acquisitions, like the purchase of Brammer Bio, have bolstered its capabilities in gene therapy manufacturing. The company is poised for robust growth, capitalizing on the rising demand for biopharmaceuticals and innovative therapies​.

Merck KGaA is a significant contributor to the single-use bioprocessing sector, providing solutions such as filtration assemblies, disposable mixers, and single-use bioreactors. These products are crucial for the streamlined and safe production of biologics. Merck’s focus on innovation and strategic partnerships has enhanced its product offerings and market reach. The company’s commitment to sustainability and efficient bioprocessing technologies positions it for continued growth as the demand for biopharmaceutical products increases​.

Avantor Inc. is a key player in the single-use bioprocessing market, offering a range of products including media bags, filtration assemblies, and single-use systems. These solutions are essential for efficient biopharmaceutical production, minimizing contamination risks and operational costs. Avantor’s strategic focus on innovation and customer-centric solutions has strengthened its market position. The company’s dedication to improving bioprocessing efficiency and expanding its product portfolio supports its growth trajectory in the competitive single-use bioprocessing sector​.

Single-use Bioprocessing Market Key Players:

  • Sartorius AG
  • Danaher Corp.
  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • Avantor Inc.
  • Eppendorf SE
  • Corning Inc.
  • Boehringer Ingelheim International GmbH
  • Lonza
  • Infors AG
  • PBS Biotech Inc.

Single-use Bioprocessing Market Report Scope >> Market Value (2023): USD 27.6 Billion || Forecast Revenue (2033): USD 139.6 Billion || CAGR (2024-2033): 17.6% || Base Year Estimation: 2023 || Historic Period: 2019-2022 || Forecast Period: 2024-2033.

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Last Updated: 16-May-2024