Resolution Therapeutics Announces Upcoming Scientific Presentations at EASL Congress 2024

– Late-breaking abstract on extended follow-up data from the MATCH Phase 2 trial accepted for poster presentation –

– Poster presentation on new data highlighting the Company’s discovery platform to differentiate, engineer and cryopreserve macrophages for therapeutic use –

Edinburgh and London, UK, 29 May 2024 – Resolution Therapeutics Limited (“Resolution” or “Company”), a clinical-stage biopharmaceutical company pioneering engineered autologous macrophage cell therapies to transform the treatment of inflammatory organ diseases, today announces two abstracts have been accepted as poster presentations at the European Association for the Study of the Liver (EASL) Congress 2024, which is being held in Milan, Italy between June 5-8, 2024.

The first is a late-breaking abstract showcasing extended follow-up data from the MATCH Phase 2 trial.  The second abstract highlights new data on Resolution’s discovery platform to differentiate, engineer and cryopreserve macrophages for therapeutic use in patients with end-stage liver disease (ESLD).

Amir Hefni, Ph.D., Chief Executive Officer of Resolution said: “Building on the MATCH Phase 2 data presented at the AASLD Annual Meeting last November, these poster presentations at the EASL Congress 2024 further validate the transformative potential of macrophage cell therapy and reinforce the strength of our discovery platform which enabled the development of Resolution’s improved engineered macrophages. We aim to bring the therapeutic potential of engineered macrophages closer to patients with our first-in-human Phase 1/2 EMERALD study in ESLD, our first target indication, starting in the third quarter of this year.”

Details of the EASL Congress 2024 poster presentations are as follows:

Poster ID: LBP-007

Title: Beneficial effects of autologous macrophage therapy on clinical outcomes in patients with compensated cirrhosis: extended follow-up data from a randomized controlled Phase 2 trial

Session: Late breaker posters

Date and Time: Wednesday, June 5, 2024, 8:30 a.m. CEST

Presenter: Dr Paul Brennan, University of Dundee

Poster ID: WED-090

Title: Developing a discovery platform for engineered macrophage cell therapies for end stage liver disease

Session: Poster - Cirrhosis and its complications: Experimental and pathophysiology

Date and Time: Wednesday, June 5, 2024, 8:30 a.m. CEST

Presenter: Lara Campana, Ph.D., Vice President, Research Operations at Resolution Therapeutics

Additionally, Stuart Forbes, Ph.D., Professor of Transplantation and Regenerative Medicine at the University of Edinburgh and Co-founder of Resolution, will deliver a presentation titled “Macrophage therapy for liver disease” on Tuesday, June 4, 2024, at 5:00 p.m. CEST at the 3rd International Symposium on Regenerative Hepatology organized by the EASL Regenerative Hepatology Consortium in Milan, Italy.

For more information about the EASL Congress 2024, including details related to accepted abstracts and presentations, please visit its website. Additional information about the 3rd International Symposium on Regenerative Hepatology can be accessed on its website.