Today Stories

Boehringer Ingelheim and researchers from the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard have agreed to collaborate on a project to tackle the urgent and unmet needs of people living with mental health conditions. The collaboration will focus on developing first-in-class treatments that address sleep disturbances associated with cognitive impairment in mental health conditions such as schizophrenia or mood disorders, which have a substantial impact on those affected, but also on their care partners and families. One in eight people are currently living with a serious mental health condition worldwide, and one in two people will experience such a condition in their lifetime. Cognitive impairment is one of the core characteristics of mental health co…

Lund, Sweden – SmiLe company Aligned Bio has successfully completed a financing round, securing SEK 19.4 million to accelerate the development and scale up its nanowire production technology. The company has been accepted into the SmiLe incubator program.  The nanotechnology company Aligned Bio has completed a new share issue to take its unique platform for manufacturing semiconductor nanowires toward commercialization. Both existing shareholders and new investors, including SmiLe Inject Capital, participated in the financing round.  What makes Aligned Bio’s technology unique is its ability to detect individual molecules, significantly improving sensitivity in the analysis of biomolecules. The production of nanowires also becomes simpler and thus more cost-effective than with existing tech…

Partnership to Combine AbbVie's Oncology Expertise with EvolveImmune's Proprietary EVOLVE T-Cell Engager Platform to Develop Novel Multispecific Therapeutic Antibodies for Cancer NORTH CHICAGO, Ill. and BRANFORD, Conn., Oct. 31, 2024 /PRNewswire/ -- AbbVie (NYSE: ABBV) and EvolveImmune Therapeutics, an immuno-oncology company developing next-generation biotherapeutics to overcome the therapeutic challenges of cancer cell resistance to current immunotherapies, today announced a collaboration and option-to-license agreement to develop multispecific biologics for multiple targets in oncology. The discovery partnership will leverage EvolveImmune's T-cell engager platform to develop novel antibody-based therapies for solid and hematologic malignancies. EvolveImmune's proprietary EVOLVE platfor…

Abbott's world-leading1 FreeStyle Libre 2 and 3 systems for people living with diabetes are now the only continuous glucose monitoring sensors 2 in the U.S. that users do not need to remove during common imaging procedures like X-rays, CT scans and MRIs* ABBOTT PARK, Ill. – Oct. 30, 2024 – Abbott today announced that its FreeStyle Libre 2 and 3 systems can now be worn during common imaging procedures, such as X-rays, CT scans and MRIs*. The U.S. Food and Drug Administration (FDA) cleared the removal of the imaging contraindication, making Abbott’s systems the first and only patient-applied continuous glucose monitoring (CGM) sensors approved for these screenings. People who use FreeStyle Libre 2 and 3 systems rely on their CGM sensors to make important decisions about their diabetes, inc…

The collaboration aims to discover and develop molecular glue degrader clinical candidates for priority targets to Biogen. Collaboration leverages Neomorph's leading molecular glue discovery platform and Biogen’s deep expertise in Alzheimer’s, rare, and immunological diseases. CAMBRIDGE, Mass. and SAN DIEGO, Calif., Oct. 29, 2024 (GLOBE NEWSWIRE) -- Biogen Inc. (Nasdaq: BIIB) and Neomorph Inc. announced a research collaboration to discover and develop molecular glue degraders for priority targets in Alzheimer’s, rare neurological, and immunological diseases. As part of the collaboration, the companies aim to utilize Neomorph's proprietary molecular glue discovery platform to accelerate the identification and validation of novel small molecule therapeutic molecular glue degraders. Small m…

Aliada's lead compound, ALIA-1758, an anti-pyroglutamate amyloid beta (3pE-Aβ) antibody, is a potential best-in-class therapy for Alzheimer's disease Acquisition also allows AbbVie to utilize Aliada's novel blood-brain barrier (BBB)-crossing technology to enhance discovery and development efforts across neuroscience NORTH CHICAGO, Ill. and BOSTON, Oct. 28, 2024 /PRNewswire/ -- AbbVie (NYSE: ABBV) and Aliada Therapeutics today announced a definitive agreement under which AbbVie will acquire Aliada, a biotechnology company advancing therapies using a novel blood-brain barrier (BBB)-crossing technology to address challenging central nervous system (CNS) diseases. Aliada's lead investigational asset utilizing this delivery technology, ALIA-1758, is an anti-pyroglutamate amyloid beta (3pE-Aβ…

INDIANAPOLIS, IN / ACCESSWIRE / October 28, 2024 / 3Aware, a pioneer in real-world evidence (RWE) solutions for the medical device industry, is pleased to announce a strategic partnership with RQM+, a leading global MedTech service provider. This collaboration marks a significant step in enhancing regulatory compliance and fostering innovation within the MedTech sector. The partnership will combine 3Aware's advanced aiSurveillance technology with RQM+'s comprehensive regulatory expertise to offer an integrated approach to post-market surveillance and compliance for medical device and IVD manufacturers. This synergy aims to transform how companies meet rigorous regulatory requirements while accelerating label expansion and time to market for new and innovative medical devices. "Joining forc…

The first-of-its-kind TEAM-HF study seeks to improve clinical outcomes in patients with worsening heart failure Trial establishes new, objective criteria to identify patients most at risk for developing end-stage heart failure and potentially offer life-saving therapeutic options sooner in their disease progression ABBOTT PARK, Ill., Oct. 24, 2024 /PRNewswire/ -- Abbott (NYSE: ABT) today announced a new, first-of-its-kind clinical trial designed to improve outcomes in patients with worsening heart failure who could benefit from advanced therapy options. The TEAM-HF trial, which is planned to enroll up to 850 patients across 75 sites worldwide, will measure pulmonary artery pressures (PAP) using Abbott's CardioMEMS™ HF System to objectively identify advanced heart failure patients at high…

Key scientific achievements drive the expansion of the pipeline of molecular glue degraders in fields beyond oncology Evotec receives a US$ 50 m payment from Bristol Myers Squibb; potential programme-based milestone payments contribute to the deal value Hamburg, Germany, 23 October 2024:Evotec SE (Frankfurt Stock Exchange: EVT, SDAX/TecDAX, ISIN: DE0005664809; NASDAQ: EVO) today announced progress within the Company’s strategic partnership with Bristol Myers Squibb relating to building a molecular glue-based pipeline. Key scientific achievements drive the expansion of the pipeline of molecular glue degraders in fields beyond oncology, triggering a programme-based payment of US$ 50 m to Evotec. Based on potential programme-based milestones, the expansion contributes to the deal value. Evo…

Sandwich, Kent, UK / 23 October 2024 / In a bid to enable future success and growth, ten entrepreneurial life science and technology businesses have begun the immersive Discovery Spark programme, with a prize package worth over £50,000 up for grabs. Based in Sandwich, Kent,  Discovery Park is a leading science and innovation campus offering a range of impressive facilities for dynamic start-ups through to global corporations. Now in its third iteration, the Discovery Spark programme equips early stage life science and technology businesses with the skills and tools to lay healthy foundations in their business, refine their commercial strategy and achieve investor readiness. The ten entrepreneurial businesses securing a coveted spot on this cohort and looking to advance their organisation a…

The Cambridge-GSK Translational Immunology Collaboration (CG-TIC) brings together GSK’s expertise in the science of the immune system, AI and clinical development with Cambridge’s complementary expertise GSK is investing more than £50 million in the CG-TIC to further accelerate research and development in kidney and respiratory diseases GSK plc (LSE/NYSE: GSK) announced it is investing £50 million into a major new five-year collaboration with the University of Cambridge and Cambridge University Hospitals, to accelerate research and development into immune-related diseases. The collaboration, which will be called the Cambridge-GSK Translational Immunology Collaboration (CG-TIC), builds on GSK and Cambridge University’s existing scientific relationship and will aim to find ways to more pre…

Sanofi and CD&R enter exclusive negotiations to transfer a 50% controlling stake in Opella with Sanofi to remain a significant shareholder With 11,000 talented and passionate people bringing iconic brands to life, Opella poised to ignite new bold development journey Sanofi to become a focused science-driven biopharma delivering innovative medicines and vaccines to patients Sanofi 2024 business EPS guidance upgraded today Paris, October 21, 2024. Sanofi and CD&R announce today a plan to join forces to fuel Opella’s ambitions as a French-headquartered, global consumer healthcare champion. Sanofi and CD&R have entered exclusive negotiations for the potential sale and purchase of a 50% controlling stake in Opella. This new step in Opella’s journey paves the way for the creation o…

Sanofi and Orano join forces to develop next-generation radioligand medicines Paris, October 17, 2024. Sanofi and Orano Med, a subsidiary of the Orano Group and a pioneer in the development of targeted alphatherapies in oncology, have entered into an agreement to combine their expertise in the fight against rare cancers and further accelerate the development of next-generation radioligand medicines. Building on the expertise and radioligand pipeline of Orano Med, Sanofi and Orano will invest in a new entity, operating under the Orano Med brand, and focusing on the discovery, design, and clinical development of next-generation radioligand therapies (RLTs) based on lead-212 (212Pb) alpha-emitting isotopes. This agreement follows Sanofi’s announcement of an exclusive licensing agreement with…

CHICAGO, IL (October 15, 2024) – Advanced Clinical, a privately-held clinical development and strategic resourcing organization committed to providing a better clinical experience across the drug development journey, has been honored with the American Staffing Association’s Elevate Award for having one of the best job training programs in the U.S. staffing and recruiting industry. “We are deeply honored to receive this recognition for our ACCEL Talent Development Program,” said Julie Ross, President and CEO of Advanced Clinical. “At the heart of our mission is the belief that empowering individuals with the right opportunities and skill sets can truly enhance lives. This award is a testament to the dedication and innovation of our team, who have worked tirelessly to create a supportive and…

Prestigious award honors top pharmaceutical facility projects each year; showcases impressive engineering feats and technological innovation NORTH BETHESDA, Md., Oct. 14, 2024 /PRNewswire-PRWeb/ -- The International Society for Pharmaceutical Engineering (ISPE) has recognized Eli Lilly Kinsale Limited as the Overall Winner of the 2024 Facility of the Year Awards (FOYA) for its IE2b facility based in Kinsale, Ireland. The winner was announced and formally recognized during ISPE's FOYA Banquet and Awards Celebration held in conjunction with the 2024 ISPE Annual Meeting & Expo in Orlando, Florida. The vision for Eli Lilly's IE2b project was to marry innovative, advanced technologies into a first-of-its-kind hybrid manufacturing platform in order to optimize synthetic peptide production fo…

Bracknell, UK. 14th October 2024: PharmiWeb.Jobs, the leading global life sciences job board, is excited to announce the launch of its redesigned website for life science recruiters and talent acquisition teams. With new features, content, and improved navigation, the new site presents a one-stop-shop for anyone recruiting within the industry looking for ways to enhance their hiring and keep up with the latest industry trends. As well as a more streamlined user experience, the new site includes a more in-depth overview of PharmiWeb’s history, mission, vision, and values, providing deeper insights into the company’s purpose and dedication to the life sciences. It also provides easier access to valuable resources including industry reports, previous and upcoming webinars, newsletter subscrip…

Enrollment completed ahead of schedule in the global IDE for Abbott's Volt™ PFA System Global FOCALFLEX trial now underway for Abbott's TactiFlex™ Duo Ablation Catheter, Sensor Enabled™ Advisor™ HD Grid X Mapping Catheter, Sensor Enabled™, receives U.S. Food and Drug Administration clearance, begins commercial launch ABBOTT PARK, Ill., Oct. 10, 2024 /PRNewswire/ -- Abbott (NYSE: ABT) announced today it has achieved new major milestones to support the company's growing suite of pulsed field ablation (PFA) solutions in electrophysiology: early completion of enrollment in the VOLT-AF IDE Study supporting the Volt™ PFA System, and the launch of the FOCALFLEX trial to assess the company's TactiFlex™ Duo Ablation Catheter, Sensor Enabled™ (SE), which will be used in the treatment of pati…

BERLIN – October 7, 2024 – EVERSANA, a leading provider of global commercial services to the life sciences industry, today announced the continued growth of its European footprint with a new office in Berlin, Germany, Europe’s largest pharmaceutical market. The office opening represents the company’s continued investment in global commercial operations, including expanded critical infrastructure and commercial launch services across Europe. The location is the latest addition to EVERSANA’s real estate portfolio, including office locations in more than fifteen countries worldwide. The new facility is located in the Carre am Schnikelplatz building in the heart of Berlin and will serve as a destination for employee and client meetings throughout the region. “Over the years we have made smart…

AstraZeneca has entered into an exclusive license agreement with CSPC Pharmaceutical Group Ltd (CSPC) to advance the development of an early stage, novel small molecule Lipoprotein (a) (Lp(a)) disruptor that has the potential to offer additional benefits for patients with dyslipidaemia. This asset further strengthens the company’s cardiovascular portfolio to help address the major risk factors driving chronic cardiovascular disease.   Under the terms of the agreement, AstraZeneca will receive access to CSPC’s pre-clinical candidate small molecule, YS2302018, an oral Lp(a) disruptor, with the aim of developing this as a novel lipid-lowering therapy with potential in a range of cardiovascular disease indications alone or in combination, including with the oral small molecule PCSK9 inhibito…

Company Launches Accelerator™ Drug Development, 360° Contract Development and Manufacturing Organization (CDMO) and Contract Research Organization (CRO) Services that highlight advanced capabilities to help pharmaceutical and biotech customers solve global health challenges with new medicines and vaccines MILAN--(BUSINESS WIRE)-- Thermo Fisher Scientific Inc., the world leader in serving science, will showcase its latest innovations enabling the molecule-to-medicine journey and host a series of sessions that feature industry developments during CPHI Milan 2024, Oct. 8-10, in Milan, Italy. Leaders and experts from the company will be present at conference booth #7B18 to discuss how Thermo Fisher is supporting biotechnology and pharmaceutical companies across indications, modalities, sizes a…