Articles

In the field of pharmaceutical marketing, artificial intelligence (AI) has already shown its potential to enable companies to create more targeted and data-driven campaigns, improve customer engagement, and optimise operations. With the field facing mounting pressure from the increased demand for personalised medicine, regulatory complexities, and growing competition, AI has emerged as a critical tool for companies to stay competitive.
In the field of pharmaceutical marketing, artificial intelligence (AI) has already shown its potential to enable companies to create more targeted and data-driven campaigns, improve customer engagement, and optimise operations. With the field facing mounting pressure from the increased demand for personalised medicine, regulatory complexities, and growing com…

Recent findings presented at the 2024 World Conference on Lung Cancer in San Diego once more highlighted the huge potential of artificial intelligence (AI) in healthcare and life sciences. The study found that AI can help detect pulmonary nodules which could develop into early-stage lung cancers – before symptoms are even present.
Recent findings presented at the 2024 World Conference on Lung Cancer in San Diego once more highlighted the huge potential of artificial intelligence (AI) in healthcare and life sciences. The study found that AI can help detect pulmonary nodules which could develop into early-stage lung cancers – before symptoms are even present. Despite its sophistication and promise, there remains a roadblock to the broader implementation of AI in healthcare. Traditionally, AI…

Ghost job listings appear to advertise available roles, but in reality, don’t reflect an actively available position. Whilst many companies are hesitant to admit to posting ghost job listings, it was recently reported by Fortune that Around 17% of recruiters say up to three-quarters of their job posts aren’t genuine, 21.5% of recruiters say ghost jobs account for half of all positions they post 36% of recruiters say a quarter of their postings are fake or already filled.
Ghost job listings appear to advertise available roles, but in reality, don’t reflect an actively available position. Whilst many companies are hesitant to admit to posting ghost job listings, it was recently reported by Fortune that: Around 17% of recruiters say up to three-quarters of their job posts aren’t genuine 21.5%…

Microorganisms have different growth requirements. When culturing them in the laboratory, it is essential to take note of these conditions because these are needed to be replicated in order to successfully grow microbial cultures in the laboratory. As mentioned in the previous article, one of the conditions needed to be taken into consideration is the oxygen requirement of the microorganisms. Some common microorganisms such as Escherichia coli and Bacillus sp. are usually cultured in the laboratory and used as reference organisms in microbiological studies. These organisms are relatively easier to culture because they are aerobic organisms and do not require complex culture conditions for growth.
  Microorganisms have different growth requirements. When culturing them in the laboratory…

When a ribosome is affixed to the polypeptide (protein) it is making, the ribosome-nascent chain complex (RNC) is the compilation of molecules that make up the ribosome. One of several methods can be used to halt the synthesis of the nascent polypeptide. RNCs are made and purified in labs to study the dynamics, biochemistry, folding, and interactions that the ribosome and proteins undergoing synthesis.
  When a ribosome is affixed to the polypeptide (protein) it is making, the ribosome-nascent chain complex (RNC) is the compilation of molecules that make up the ribosome. One of several methods can be used to halt the synthesis of the nascent polypeptide. RNCs are made and purified in labs to study the dynamics, biochemistry, folding, and interactions that the ribosome and proteins unde…

Analysis of variance (ANOVA) is a powerful statistical method that allows researchers to compare the means of two or more groups and determine if they are significantly different. It is a popular tool for testing hypotheses in a variety of fields in biology, including ecology, genetics, physiology, and biochemistry. In this article, we will explore how to choose the right type of ANOVA for your research question and design an experiment using ANOVA in several steps.
  Analysis of variance (ANOVA) is a powerful statistical method that allows researchers to compare the means of two or more groups and determine if they are significantly different. It is a popular tool for testing hypotheses in a variety of fields in biology, including ecology, genetics, physiology, and biochemistry.…

Next-generation sequencing, PacBio SMRT sequencing, and Nanopore sequencing, can generate numerous sequence data in a single run. Raw reads or assembled sequence need to be submitted to public sequence repository (DDBJ/ENA/GenBank - INSDC), which is required by the overwhelming majority of journals as accession numbers of theses sequence data should be presented in in the published papers. The submission portal (https://submit.ncbi.nlm.nih.gov/) is a programmatic interface for users to submit sequence data and download others’ sequence data.
Submission of sequence data to NCBI archives Next-generation sequencing, PacBio SMRT sequencing, and Nanopore sequencing, can generate numerous sequence data in a single run. Raw reads or assembled sequence need to be submitted to public seque…

Enter metagenomic next-generation sequencing (mNGS), an all-encompassing and precise approach for microbial detection and taxonomic characterization. While numerous studies and case reports underscore the efficacy of mNGS in enhancing the diagnosis, treatment, and tracking of infectious diseases, formidable obstacles still lie on the path forward.
  In recent years, the landscape of sequencing technologies has undergone a transformative shift, transitioning from research settings to the realm of clinical laboratories. This transformation has been catalyzed by rapid technological advancements and significant cost reductions. Despite a multitude of microorganisms known to inflict human infections, prevailing diagnostic techniques merely scratch the surface, leaving a vast array of pathog…

Protein labeling refers to the process of attaching a detectable tag or marker to a protein. This can be achieved through various chemical, enzymatic, genetic, or isotopic methods. The purpose of protein labeling is to make proteins traceable, enabling detailed analysis of their function, structure, and interactions within biological systems.
Protein labeling refers to the process of attaching a detectable tag or marker to a protein. This can be achieved through various chemical, enzymatic, genetic, or isotopic methods. The purpose of protein labeling is to make proteins traceable, enabling detailed analysis of their function, structure, and interactions within biological systems.   Labeling proteins plays a vital role in many biological experiments, particularly in understanding cellu…

Cell lysis refers to the process of breaking down the cell membrane to release cellular contents, including proteins, nucleic acids, and other biomolecules. Protein extraction is the subsequent step where proteins are separated from other cellular components for analysis or further manipulation. These processes are crucial for understanding cellular mechanisms, identifying potential biomarkers, and developing therapeutic strategies.
  Cell lysis refers to the process of breaking down the cell membrane to release cellular contents, including proteins, nucleic acids, and other biomolecules. Protein extraction is the subsequent step where proteins are separated from other cellular components for analysis or further manipulation. These processes are crucial for understanding cellular mecha…

Stable isotope labeling is a sophisticated technique that involves incorporating stable isotopes into molecules to trace and analyze various biological and chemical processes. Unlike radioactive isotopes, which decay over time and emit radiation, stable isotopes remain constant and do not pose the same safety risks. This stability allows for long-term studies and precise measurements without the complications associated with radiation.
What is Stable Isotope Labeling? Stable isotope labeling is a sophisticated technique that involves incorporating stable isotopes into molecules to trace and analyze various biological and chemical processes. Unlike radioactive isotopes, which decay over time and emit radiation, stable isotopes remain constant and do not pose the same safety risks. This stabi…

Therapeutic monoclonal antibodies (mAbs) are a class of antibody drugs that are highly uniform and have pharmacological effects against a single epitope obtained through molecular biology.
  Therapeutic monoclonal antibodies (mAbs) are a class of antibody drugs that are highly uniform and have pharmacological effects against a single epitope obtained through molecular biology.   In the process of new drug development, the study of pharmacokinetics is of great significance. The result can be used to guide the screening and development of drugs, and support the evaluation of their safety and the design of clinical drug delivery protocol.   Pharmacokinetic characteristics are composed of and determined by drug absorption, distribution, metabolism and excretion. The structure, ph…

Vaccines have been essential in disease prevention, and the requirements for vaccine quality continue to increase. The application of advanced separation and purification technologies during the preparation of traditional and new vaccines is an effective means to improve vaccine efficacy and reduce side effects.
Vaccines have been essential in disease prevention, and the requirements for vaccine quality continue to increase. The application of advanced separation and purification technologies during the preparation of traditional and new vaccines is an effective means to improve vaccine efficacy and reduce side effects. Here are some commonly used purification methods:   Centrifugal Ultracentrifugation The sample particles sink at a certain speed, determined by their size, shape, and…

The role of advanced diagnostics in functional medicine. Specialty labs are making a difference in the industry due to the cutting-edge technology they are implementing. The shift towards personalized medicine is happening now and the insights gained from functional medicine diagnostics are leading to better patient care.
Advancing Diagnostics in Specialty Medicine: Insights from Functional Medicine Testing As the healthcare industry increasingly embraces personalized medicine, advanced diagnostics is important in functional medicine’s ability to support these efforts. Functional medicine, which focuses on identifying the root causes of diseases through a holistic approach, is a growing area of interest in both clinical settings and the pharmaceutical/biotech sectors. Understanding the Role…

Enzymes, biological catalysts integral to metabolic processes, have increasingly become central to numerous industrial applications. Their inherent specificity, efficiency under mild conditions, and eco-friendly nature present compelling advantages over conventional chemical catalysts, prompting widespread adoption in diverse industries. This article seeks to elucidate the multifaceted roles of enzymes in industrial processes, highlighting their biochemical mechanisms and potential for innovation and improvement.
Enzymes, biological catalysts integral to metabolic processes, have increasingly become central to numerous industrial applications. Their inherent specificity, efficiency under mild conditions, and eco-friendly nature present compelling advantages over conventional chemical cataly…

Ovalbumin, also known as albumin or OVA, is the most abundant protein found in egg white, accounting for approximately 54% of its total protein content. This versatile glycoprotein has captivated researchers and industry professionals alike due to its unique properties and wide-ranging applications. In this article, we'll explore the structure, functions, and diverse uses of ovalbumin in various fields.
  Ovalbumin, also known as albumin or OVA, is the most abundant protein found in egg white, accounting for approximately 54% of its total protein content. This versatile glycoprotein has captivated researchers and industry professionals alike due to its unique properties and wide-ranging applications. In this article, we'll explore the structure, functions, and diverse uses of ovalbumin…

Elastase is a powerful enzyme that plays a critical role in various biological processes, both in physiological and pathological contexts. It belongs to the family of serine proteases, which are enzymes characterized by a unique serine residue in their active site. This enzyme is known for its ability to degrade elastin, a key protein that provides elasticity and resilience to tissues such as skin, lungs, and blood vessels. Understanding the functions and implications of elastase is crucial in biochemistry and medicine, as it has a significant impact on both health and disease.
Elastase is a powerful enzyme that plays a critical role in various biological processes, both in physiological and pathological contexts. It belongs to the family of serine proteases, which are enzymes characterized…

Ribonucleases (RNases) represent a critical class of enzymes with a principal role in the degradation of RNA, crucial for maintaining cellular homeostasis and regulating gene expression. By cleaving RNA molecules, RNases are integral to numerous biological processes, ranging from RNA maturation to the innate immune response against RNA viruses. In this exploration, we delve into the multifaceted nature of ribonucleases, examining their structure, function, and potential in biotechnology.
Ribonucleases (RNases) represent a critical class of enzymes with a principal role in the degradation of RNA, crucial for maintaining cellular homeostasis and regulating gene expression. By cleaving RNA molecules, RNases are integral to numerous biological processes, ranging from RNA maturation to the innat…

Air transport is a critical lifeline for the life sciences and health care industries, ensuring the timely delivery of essential products like medicines and lab samples worldwide. Whether transporting temperature-sensitive biologics or coordinating international clinical trials, life sciences companies rely heavily on the efficiency of air logistics.
Air transport is a critical lifeline for the life sciences and health care industries, ensuring the timely delivery of essential products like medicines and lab samples worldwide. Whether transporting temperature-sensitive biologics or coordinating international clinical trials, life sciences companies rely heavily on the efficiency of air logistics. However, when air transport is disrupted — whether by weather, geopolitical tensions, or logist…

Starting a career in clinical research is an exciting yet challenging step. Whether you’re fresh out of university or transitioning from another field, working in clinical research offers a dynamic environment with plenty of opportunities for growth and learning, as well as an incredibly rewarding career path.
Starting a career in clinical research is an exciting yet challenging step. Whether you’re fresh out of university or transitioning from another field, working in clinical research offers a dynamic environment with plenty of opportunities for growth and learning, as well as an incredibly rewarding career path. Here, we explore the key aspects of entry-level roles in clinical research, looking at the types of roles on offer, what to expect in your first job and the skills you’ll need t…